Interactor 1: Q9VNW6 (Q9VNW6)
Delta-1-pyrroline-5-carboxylate synthase [Includes: Glutamate 5-kinase (GK) (EC 2.7.2.11) (Gamma-glutamyl kinase); Gamma-glutamyl phosphate reductase (GPR) (EC 1.2.1.41) (Glutamate-5-semialdehyde dehydrogenase) (Glutamyl-gamma-semialdehyde dehydrogenase)]
Gene: P5CS

Interactor 2: Q9VNW6 (Q9VNW6)
Delta-1-pyrroline-5-carboxylate synthase [Includes: Glutamate 5-kinase (GK) (EC 2.7.2.11) (Gamma-glutamyl kinase); Gamma-glutamyl phosphate reductase (GPR) (EC 1.2.1.41) (Glutamate-5-semialdehyde dehydrogenase) (Glutamyl-gamma-semialdehyde dehydrogenase)]
Gene: P5CS

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 1.00 0.647

The method score is based on:

Property Details
Experiments 32317150
Identification Methods pull down
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains AA_kinase~AA_kinase, Aldedh~Aldedh
Common GO terms GO:0004349 - glutamate 5-kinase activity
GO:0004350 - glutamate-5-semialdehyde dehydrogenase activity
GO:0005524 - ATP binding
GO:0005739 - mitochondrion
GO:0006561 - proline biosynthetic process
and 2 others

more...

Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 776
Dm

1 776
+ Hs
+ At
+ Sc
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Ec
+ Sc
+ Sc
+ Sc
+ Sc
+ Dr

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Last updated: 15 Jul 2024