HitPredict

Interactor 1: DRM (Q9VQS6)
Protein drumstick
Gene: DRM

Interactor 2: RX (Q9W2Q1)
Retinal homeobox protein Rx (DRx) (DRx1)
Gene: RX

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.60	0.541

Property	Details
Experiments	30995488
Identification Methods	two hybrid, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 81 Dm			1 873
+	Dm
		65369 DRM_DROME (1-81): 3.06e-31: 105: 100.00		A8DYR8_DROME (417-720): 1.04e-36: 145: 20.94
+	Dm
		1372733 DRM_DROME (1-81): 3.06e-31: 105: 100.00		Q9XZU0_DROME (520-862): 2.16e-35: 140: 24.43
+	Dm
		1249952 DRM_DROME (1-81): 3.06e-31: 105: 100.00		Q8T0V5_DROME (520-862): 4.83e-35: 139: 24.43
+	Hs
		575278 EGR1_HUMAN (2-81): 1.96e-22: 90.9: 21.18		PAX6_HUMAN (470-730): 2.83e-38: 150: 28.89
+	Mm
		434886 EGR1_MOUSE (2-81): 2.89e-22: 90.1: 21.18		PITX1_MOUSE (450-753): 5.73e-39: 149: 22.88
+	Hs
		575368 EGR1_HUMAN (2-81): 1.96e-22: 90.9: 21.18		PITX1_HUMAN (450-753): 1.34e-36: 142: 22.88
+	Dm
		111997 SOB_DROME (20-74): 3.7e-22: 90.2: 60.00		L0MPR7_DROME (466-758): 8.69e-35: 141: 24.52
+	Hs
		563558 ZNF24_HUMAN (24-81): 2.72e-27: 102: 32.76		PAX7_HUMAN (507-816): 2.37e-28: 122: 25.72
+	Hs
		540837 SP4_HUMAN (1-49): 2.66e-18: 78.9: 30.61		PO2F1_HUMAN (296-855): 4.35e-31: 132: 13.26
+	Hs
		434919 SP1_HUMAN (2-49): 3.77e-17: 75.8: 25.00		PO2F1_HUMAN (296-855): 4.35e-31: 132: 13.26
+	Dm
		1359812 SOB_DROME (20-74): 3.7e-22: 90.2: 60.00		Q9V490_DROME (466-804): 1.29e-26: 117: 21.33
+	Hs
		641511 ZKSC4_HUMAN (51-81): 1e-09: 54.8: 29.03		PAX6_HUMAN (470-730): 2.83e-38: 150: 28.89
+	Hs
		822658 ZKSC4_HUMAN (51-81): 1e-09: 54.8: 29.03		LHX1_HUMAN (467-766): 1.6e-31: 129: 19.41
+	Hs
		620188 ZKSC4_HUMAN (51-81): 1e-09: 54.8: 29.03		PAX7_HUMAN (507-816): 2.37e-28: 122: 25.72
+	Hs
		1077276 ZN300_HUMAN (4-81): 2.37e-10: 56.3: 14.82		ALX1_HUMAN (405-670): 4.3e-29: 120: 25.75
+	Hs
		968002 SALL4_HUMAN (28-73): 3.92e-10: 55.9: 41.30		PO5F1_HUMAN (368-665): 2.42e-27: 116: 17.33
+	Hs
		156120 SP1_HUMAN (2-49): 3.77e-17: 75.8: 25.00		PHX2A_HUMAN (525-588): 6.92e-20: 92.8: 68.75
+	Hs
		505249 EGR2_HUMAN (7-81): 2.64e-19: 81.6: 19.48		ZFHX4_HUMAN (293-731): 2.64e-13: 76.7: 13.51
+	Hs
		505222 EGR2_HUMAN (7-81): 2.64e-19: 81.6: 19.48		ZFHX3_HUMAN (357-820): 1.05e-10: 68.2: 13.19
+	Hs
		1281579 ZKSC4_HUMAN (51-81): 1e-09: 54.8: 29.03		VSX1_HUMAN (511-588): 4.12e-19: 92: 57.65