HitPredict

Interactor 1: MXT (Q9VR35)
Eukaryotic translation initiation factor 4E-binding protein Mextli
Gene: MXT

Interactor 2: Q9VSB6 (Q9VSB6)
eIF-4F 25 kDa subunit
Gene: eIF4E5

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.600

Property	Details
Experiments	14605208, 22036573
Identification Methods	two hybrid, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003743 - translation initiation factor activity
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 653 Dm			1 232
+	Dm
		820462 MXT_DROME (1-653): 0: 1232: 100.00		IF4E_DROME (2-232): 1.43e-94: 279: 53.85
+	Dm
		1372879 MXT_DROME (1-653): 0: 1232: 100.00		Q9VRY0_DROME (1-232): 3.5e-94: 276: 51.29
+	Dm
		1372882 MXT_DROME (1-653): 0: 1232: 100.00		Q9W5B3_DROME (45-232): 1.68e-89: 271: 52.63
+	Dm
		1372881 MXT_DROME (1-653): 0: 1232: 100.00		Q9VSG1_DROME (49-232): 1.57e-88: 263: 52.72
+	Ce
		247884 MXT_CAEEL (28-321): 3.69e-142: 425: 30.15		IF4E3_CAEEL (33-232): 1.55e-84: 253: 38.79
+	Ce
		220263 MXT_CAEEL (28-321): 3.69e-142: 425: 30.15		IF4E1_CAEEL (55-232): 3.54e-82: 246: 39.36
+	Ce
		1094360 MXT_CAEEL (28-321): 3.69e-142: 425: 30.15		IF4E2_CAEEL (40-232): 9.31e-81: 243: 38.92