HitPredict

Interactor 1: MXT (Q9VR35)
Eukaryotic translation initiation factor 4E-binding protein Mextli
Gene: MXT

Interactor 2: Q9W5B3 (Q9W5B3)
eIF-4F 25 kDa subunit
Gene: eIF4E7

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.59	0.60	0.595

Property	Details
Experiments	23716590, 14605208
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003743 - translation initiation factor activity
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 653 Dm			1 429
+	Dm
		820462 MXT_DROME (1-653): 0: 1232: 100.00		IF4E_DROME (167-429): 1.65e-96: 291: 51.71
+	Dm
		1372879 MXT_DROME (1-653): 0: 1232: 100.00		Q9VRY0_DROME (218-429): 6.37e-96: 288: 52.75
+	Dm
		1372880 MXT_DROME (1-653): 0: 1232: 100.00		Q9VSB6_DROME (238-429): 7.43e-93: 281: 52.08
+	Dm
		1372881 MXT_DROME (1-653): 0: 1232: 100.00		Q9VSG1_DROME (250-429): 1.58e-89: 273: 50.56
+	Ce
		247884 MXT_CAEEL (28-321): 3.69e-142: 425: 30.15		IF4E3_CAEEL (250-429): 2.6e-88: 270: 44.32
+	Ce
		220263 MXT_CAEEL (28-321): 3.69e-142: 425: 30.15		IF4E1_CAEEL (242-429): 1.74e-87: 266: 38.07
+	Ce
		1094360 MXT_CAEEL (28-321): 3.69e-142: 425: 30.15		IF4E2_CAEEL (241-429): 3.37e-84: 258: 38.89