HitPredict

Interactor 1: Q9VRJ5 (Q9VRJ5)
Charged multivesicular body protein 2b (LD36173p)
Gene: CHMP2B

Interactor 2: Q9Y162 (Q9Y162)
BcDNA.GH02678 (Vacuolar protein sorting 4, isoform A (EC 3.6.1.3)) (Vacuolar protein sorting 4, isoform B)
Gene: Vps4

Species: Drosophila melanogaster

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	22036573
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0016197 - endosomal transport
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 212 Dm			1 442
+	Hs
		208804 CHM2A_HUMAN (2-191): 6.14e-38: 132: 35.26		VPS4B_HUMAN (2-442): 5.26e-128: 379: 74.21
+	Mm
		804060 CHM2A_MOUSE (2-200): 1.25e-37: 131: 34.17		VPS4B_MOUSE (2-442): 7.61e-128: 378: 75.34
+	Dm
		1279493 Q95SH2_DROME (15-212): 9.22e-36: 126: 19.19		Q9Y162_DROME (1-442): 6.4e-129: 381: 100.00
+	Dm
		1362012 Q9VBI3_DROME (2-202): 3.45e-35: 126: 33.83		Q9Y162_DROME (1-442): 6.4e-129: 381: 100.00
+	Dm
		1248702 Q8SXB1_DROME (15-202): 6.54e-35: 125: 33.51		Q9Y162_DROME (1-442): 6.4e-129: 381: 100.00
+	Hs
		208869 CHM2A_HUMAN (2-191): 6.14e-38: 132: 35.26		VPS4A_HUMAN (7-441): 3.49e-126: 374: 73.79
+	Hs
		260145 CHM1B_HUMAN (16-210): 3e-35: 125: 15.39		VPS4B_HUMAN (2-442): 5.26e-128: 379: 74.21
+	Hs
		260164 CHM2B_HUMAN (8-209): 2.22e-34: 123: 49.27		VPS4B_HUMAN (2-442): 5.26e-128: 379: 74.21
+	Hs
		260159 CHMP5_HUMAN (2-198): 3.82e-34: 122: 14.71		VPS4B_HUMAN (2-442): 5.26e-128: 379: 74.21
+	Hs
		1185556 CHM1B_HUMAN (16-210): 3e-35: 125: 15.39		VPS4A_HUMAN (7-441): 3.49e-126: 374: 73.79
+	Hs
		1357379 CHMP3_HUMAN (5-211): 1.64e-34: 124: 26.36		VPS4A_HUMAN (7-441): 3.49e-126: 374: 73.79
+	Hs
		1357378 CHM2B_HUMAN (8-209): 2.22e-34: 123: 49.27		VPS4A_HUMAN (7-441): 3.49e-126: 374: 73.79
+	Hs
		208865 CHM2A_HUMAN (2-191): 6.14e-38: 132: 35.26		SPAST_HUMAN (62-440): 1.51e-113: 348: 36.84
+	Hs
		1185555 CHM1B_HUMAN (16-210): 3e-35: 125: 15.39		SPAST_HUMAN (62-440): 1.51e-113: 348: 36.84
+	Sc
		732854 DID4_YEAST (1-197): 2.32e-37: 131: 26.77		VPS4_YEAST (1-442): 1.8e-112: 339: 57.66
+	At
		1352475 VPS2A_ARATH (1-203): 1.75e-43: 147: 34.48		VPS4_ARATH (4-442): 9.6e-106: 322: 52.02
+	Sc
		732543 VPS24_YEAST (9-205): 8.87e-34: 122: 24.24		VPS4_YEAST (1-442): 1.8e-112: 339: 57.66
+	At
		1013169 VPS2B_ARATH (4-210): 1.28e-37: 131: 31.96		VPS4_ARATH (4-442): 9.6e-106: 322: 52.02
+	At
		98409 F4JXR3_ARATH (2-158): 8.88e-35: 125: 13.50		VPS4_ARATH (4-442): 9.6e-106: 322: 52.02
+	At
		1352776 CHM1B_ARATH (14-211): 7.29e-35: 124: 21.21		VPS4_ARATH (4-442): 9.6e-106: 322: 52.02