HitPredict

Interactor 1: Q9VRT7 (Q9VRT7)
U6 snRNA-associated Sm-like protein LSm5
Gene: BcDNA:RE60135

Interactor 2: Q9W2P5 (Q9W2P5)
RE43665p
Gene: DmelCG9344

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.70	1.00	0.839

Property	Details
Experiments	14605208, 22036573, 20353594
Identification Methods	two hybrid, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	LSM~LSM
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0005681 - spliceosomal complex GO:0005688 - U6 snRNP GO:0046540 - U4/U6 x U5 tri-snRNP complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 91 Dm			1 79
+	Hs
		912007 LSM5_HUMAN (3-91): 1.64e-33: 112: 79.78		RUXF_HUMAN (1-73): 3.03e-33: 111: 47.95
+	Hs
		912259 LSM5_HUMAN (3-91): 1.64e-33: 112: 79.78		LSM6_HUMAN (3-79): 1.38e-33: 111: 85.71
+	Hs
		1377916 LSM5_HUMAN (3-91): 1.64e-33: 112: 79.78		LSM4_HUMAN (7-79): 1.85e-31: 108: 24.32
+	Dm
		1369695 Q9VRT7_DROME (1-91): 9.35e-33: 110: 100.00		Q9VKW8_DROME (7-79): 5.22e-31: 107: 24.32
+	Dm
		1097030 Q9VRT7_DROME (1-91): 9.35e-33: 110: 100.00		RUXF_DROME (3-73): 7.31e-31: 105: 43.66
+	At
		1323924 LSM5_ARATH (7-91): 2.2e-32: 109: 65.88		LSM6A_ARATH (5-79): 1.39e-31: 106: 74.67
+	Hs
		911605 RUXE_HUMAN (7-85): 3.36e-27: 96.5: 25.30		RUXF_HUMAN (1-73): 3.03e-33: 111: 47.95
+	Hs
		911608 RUXE_HUMAN (7-85): 3.36e-27: 96.5: 25.30		LSM6_HUMAN (3-79): 1.38e-33: 111: 85.71
+	At
		1227147 Q8LAK5_ARATH (4-88): 9.61e-28: 97.7: 25.84		RUXF_ARATH (2-73): 8.43e-32: 107: 44.44
+	Hs
		911779 RUXE_HUMAN (7-85): 3.36e-27: 96.5: 25.30		LSM4_HUMAN (7-79): 1.85e-31: 108: 24.32
+	At
		1227145 Q8LAK5_ARATH (4-88): 9.61e-28: 97.7: 25.84		LSM6A_ARATH (5-79): 1.39e-31: 106: 74.67
+	At
		1352881 Q9ZV45_ARATH (4-88): 4.91e-27: 96.1: 25.84		RUXF_ARATH (2-73): 8.43e-32: 107: 44.44
+	At
		1340906 Q9ZV45_ARATH (4-88): 4.91e-27: 96.1: 25.84		LSM6A_ARATH (5-79): 1.39e-31: 106: 74.67
+	Dm
		1213201 Q8IMX8_DROME (6-88): 5.66e-26: 93.8: 20.43		Q9W2P5_DROME (1-79): 2e-32: 108: 100.00
+	Dm
		1213197 Q8IMX8_DROME (6-88): 5.66e-26: 93.8: 20.43		Q9VKW8_DROME (7-79): 5.22e-31: 107: 24.32
+	Dm
		1097029 RUXE_DROME (5-91): 6.05e-26: 93.4: 24.18		RUXF_DROME (3-73): 7.31e-31: 105: 43.66
+	Hs
		1377522 LSM5_HUMAN (3-91): 1.64e-33: 112: 79.78		LSM2_HUMAN (9-75): 1.16e-09: 51.5: 27.14
+	Dm
		1373282 Q9VRT7_DROME (1-91): 9.35e-33: 110: 100.00		Q9VTW6_DROME (9-75): 2.23e-09: 50.7: 27.14
+	Hs
		911773 RUXE_HUMAN (7-85): 3.36e-27: 96.5: 25.30		LSM2_HUMAN (9-75): 1.16e-09: 51.5: 27.14
+	Dm
		1213199 Q8IMX8_DROME (6-88): 5.66e-26: 93.8: 20.43		Q9VTW6_DROME (9-75): 2.23e-09: 50.7: 27.14