HitPredict

Interactor 1: Q9VRY0 (Q9VRY0)
eIF-4F 25 kDa subunit
Gene: eIF4E4

Interactor 2: 4EBP (Q9XZ56)
Eukaryotic translation initiation factor 4E-binding protein (4E-BP) (d4E-BP) (eIF4E-binding protein) (4E-binding protein Thor) (dThor)
Gene: Thor

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.80	0.674

Property	Details
Experiments	22833128, 15804566
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	IF4E~eIF_4EBP
Common GO terms	-
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 229 Dm			1 117
+	Mm
		926368 IF4E_MOUSE (27-229): 5.31e-99: 288: 46.60		4EBP2_MOUSE (1-117): 9.83e-53: 163: 38.33
+	Hs
		416983 IF4E_HUMAN (31-229): 1.67e-97: 285: 47.03		4EBP2_HUMAN (1-117): 3.79e-53: 164: 38.33
+	Dm
		820469 IF4E_DROME (11-229): 9.44e-98: 286: 61.54		4EBP_DROME (1-117): 2.3e-52: 162: 100.00
+	Dm
		1373550 Q9VSB6_DROME (1-229): 1.5e-94: 278: 51.29		4EBP_DROME (1-117): 2.3e-52: 162: 100.00
+	Dm
		1376673 Q9W5B3_DROME (51-229): 6.32e-90: 273: 59.44		4EBP_DROME (1-117): 2.3e-52: 162: 100.00
+	Dm
		1373609 Q9VSG1_DROME (24-229): 1.48e-91: 270: 45.63		4EBP_DROME (1-117): 2.3e-52: 162: 100.00
+	Hs
		237212 IF4E2_HUMAN (13-220): 3.27e-83: 249: 32.72		4EBP2_HUMAN (1-117): 3.79e-53: 164: 38.33
+	Rn
		926380 IF4E_RAT (27-229): 5.31e-99: 288: 46.60		4EBP1_RAT (1-117): 9.19e-36: 120: 36.13
+	Hs
		416982 IF4E_HUMAN (31-229): 1.67e-97: 285: 47.03		4EBP1_HUMAN (1-117): 3.1e-36: 121: 36.13
+	Mm
		926370 IF4E_MOUSE (27-229): 5.31e-99: 288: 46.60		4EBP1_MOUSE (1-117): 2.21e-34: 116: 36.13
+	Hs
		64108 I4E1B_HUMAN (16-229): 2.31e-91: 270: 43.78		4EBP1_HUMAN (1-117): 3.1e-36: 121: 36.13
+	Hs
		236380 IF4E_HUMAN (31-229): 1.67e-97: 285: 47.03		4EBP3_HUMAN (29-117): 3.39e-27: 97.9: 42.70
+	Hs
		237211 IF4E2_HUMAN (13-220): 3.27e-83: 249: 32.72		4EBP1_HUMAN (1-117): 3.1e-36: 121: 36.13
+	Mm
		1141831 IF4E2_MOUSE (13-220): 2.6e-83: 249: 33.18		4EBP1_MOUSE (1-117): 2.21e-34: 116: 36.13
+	Hs
		236378 IF4E2_HUMAN (13-220): 3.27e-83: 249: 32.72		4EBP3_HUMAN (29-117): 3.39e-27: 97.9: 42.70