Interactor 1: MED4 (Q9VS38)
Mediator of RNA polymerase II transcription subunit 4 (Mediator complex subunit 4) (dp34)
Gene: MED4

Interactor 2: MED21 (Q9W5P1)
Mediator of RNA polymerase II transcription subunit 21 (Mediator complex subunit 21) (dMED21) (dSRB7) (dTRAP19)
Gene: MED21

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.58 1.00 0.767

The method score is based on:

Property Details
Experiments 37061542, unassigned1513
Identification Methods two hybrid, two hybrid prey pooling approach, two hybrid array
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Med21~Med4
Common GO terms GO:0003712 - transcription coregulator activity
GO:0005634 - nucleus
GO:0006357 - regulation of transcription by RNA polymerase II
GO:0016592 - mediator complex
GO:0045893 - positive regulation of DNA-templated transcription
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 258
Dm

1 142
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024