HitPredict

Interactor 1: Q9VSM9 (Q9VSM9)
Cell division control protein
Gene: Cdc6

Interactor 2: ORC6 (Q9Y1B2)
Origin recognition complex subunit 6
Gene: ORC6

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.624

Property	Details
Experiments	32848132, 29899147
Identification Methods	pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0006270 - DNA replication initiation
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 662 Dm			1 257
+	At
		1352830 ORC1B_ARATH (32-651): 8.96e-146: 445: 18.58		ORC6_ARATH (5-233): 3.57e-92: 275: 22.58
+	Hs
		1306132 CDC6_HUMAN (87-655): 7.11e-143: 429: 32.09		ORC6_HUMAN (2-241): 3.24e-98: 288: 27.82
+	Dm
		184173 ORC1_DROME (12-650): 1.39e-114: 367: 20.64		ORC6_DROME (1-257): 5.75e-113: 326: 100.00
+	Hs
		217846 ORC4_HUMAN (230-658): 1.3e-91: 292: 14.89		ORC6_HUMAN (2-241): 3.24e-98: 288: 27.82
+	Dm
		1376237 Q9W102_DROME (246-656): 1.09e-73: 246: 13.28		ORC6_DROME (1-257): 5.75e-113: 326: 100.00
+	At
		1150972 ORC4_ARATH (243-654): 4.62e-74: 246: 16.05		ORC6_ARATH (5-233): 3.57e-92: 275: 22.58
+	Dm
		1096607 ORC5_DROME (257-490): 3.42e-37: 146: 15.77		ORC6_DROME (1-257): 5.75e-113: 326: 100.00
+	Hs
		217287 ORC5_HUMAN (262-449): 1.08e-33: 135: 16.34		ORC6_HUMAN (2-241): 3.24e-98: 288: 27.82