HitPredict

Interactor 1: UBE2C (Q9VTY6)
Ubiquitin-conjugating enzyme E2 C (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme C) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme C) (Ubiquitin carrier protein C) (Ubiquitin carrier protein vihar) (Ubiquitin-protein ligase C)
Gene: vih

Interactor 2: Q9W1E5 (Q9W1E5)
Anaphase-promoting complex subunit 2
Gene: mr

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	22417125
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	ANAPC2~UQ_con
Common GO terms	GO:0000151 - ubiquitin ligase complex GO:0031145 - anaphase-promoting complex-dependent catabolic process
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 178 Dm			1 802
+	Dm
		639413 UBCD1_DROME (33-176): 3.2e-78: 231: 37.24		Q9W1E5_DROME (1-802): 0: 756: 100.00
+	Hs
		1041136 UB2E3_HUMAN (9-176): 2.32e-75: 226: 32.54		CUL1_HUMAN (110-794): 0: 591: 13.04
+	Dm
		639393 UBCD1_DROME (33-176): 3.2e-78: 231: 37.24		CUL1_DROME (111-794): 0: 560: 13.64
+	Hs
		919897 UB2D2_HUMAN (33-176): 6.05e-79: 233: 37.93		ANC2_HUMAN (58-802): 0: 558: 36.72
+	Hs
		849326 UB2D1_HUMAN (33-176): 5.61e-79: 233: 37.24		CUL4A_HUMAN (123-790): 0: 549: 13.38
+	Hs
		895791 UB2D3_HUMAN (33-176): 4.02e-77: 228: 37.24		CUL4A_HUMAN (123-790): 0: 549: 13.38
+	Hs
		1043149 UB2E3_HUMAN (9-176): 2.32e-75: 226: 32.54		CUL4A_HUMAN (123-790): 0: 549: 13.38
+	Hs
		849324 UB2D1_HUMAN (33-176): 5.61e-79: 233: 37.24		CUL2_HUMAN (121-784): 0: 539: 10.63
+	Hs
		135959 UBE2C_HUMAN (2-174): 2.05e-70: 212: 56.65		ANC2_HUMAN (58-802): 0: 558: 36.72
+	Hs
		1042304 UB2E2_HUMAN (4-176): 2.93e-78: 233: 32.18		CUL3_HUMAN (103-791): 5.42e-179: 534: 12.04
+	Hs
		849325 UB2D1_HUMAN (33-176): 5.61e-79: 233: 37.24		CUL3_HUMAN (103-791): 5.42e-179: 534: 12.04
+	Hs
		895790 UB2D3_HUMAN (33-176): 4.02e-77: 228: 37.24		CUL2_HUMAN (121-784): 0: 539: 10.63
+	Hs
		919724 UB2D2_HUMAN (33-176): 6.05e-79: 233: 37.93		CUL3_HUMAN (103-791): 5.42e-179: 534: 12.04
+	Hs
		851812 UB2E1_HUMAN (4-176): 3.24e-76: 227: 32.76		CUL3_HUMAN (103-791): 5.42e-179: 534: 12.04
+	Hs
		1042223 UB2E3_HUMAN (9-176): 2.32e-75: 226: 32.54		CUL3_HUMAN (103-791): 5.42e-179: 534: 12.04
+	Hs
		895792 UB2D3_HUMAN (33-176): 4.02e-77: 228: 37.24		CUL4B_HUMAN (123-790): 6.41e-176: 531: 12.24
+	Hs
		828994 UBE2A_HUMAN (30-176): 4.6e-70: 210: 40.54		CUL4B_HUMAN (123-790): 6.41e-176: 531: 12.24
+	Hs
		896438 UBE2N_HUMAN (32-158): 5.34e-34: 119: 46.46		CUL3_HUMAN (103-791): 5.42e-179: 534: 12.04
+	Sp
		804458 UBC4_SCHPO (33-176): 1.17e-77: 229: 37.93		CUL3_SCHPO (490-694): 3.49e-37: 151: 21.50