HitPredict

Interactor 1: Q9VV76 (Q9VV76)
Syntaxin 8
Gene: Syx8

Interactor 2: Q9W0N6 (Q9W0N6)
LD27967p (Vesicle transport through interaction with t-SNAREs 1a)
Gene: Vti1a

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.55	1.00	0.743

Property	Details
Experiments	22036573, 19079254
Identification Methods	affinity chromatography technology, two hybrid array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	SNARE~V-SNARE_C
Common GO terms	GO:0000149 - SNARE binding GO:0005484 - SNAP receptor activity GO:0006886 - intracellular protein transport GO:0006906 - vesicle fusion GO:0031201 - SNARE complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 232 Dm			1 230
+	At
		1276968 SYP61_ARATH (6-232): 1.68e-62: 196: 17.30		VTI12_ARATH (2-221): 7.75e-62: 194: 26.36
+	At
		1351880 SYP51_ARATH (7-232): 2.01e-56: 181: 20.09		VTI11_ARATH (2-221): 4.05e-57: 182: 28.64
+	Mm
		292716 STX6_MOUSE (6-220): 2.38e-50: 166: 13.98		VTI1A_MOUSE (2-219): 2.76e-57: 182: 35.78
+	Rn
		1144364 STX6_RAT (6-221): 8.8e-51: 167: 13.92		VTI1A_RAT (2-219): 2.66e-55: 178: 35.62
+	Hs
		235202 STX10_HUMAN (6-220): 4.66e-51: 168: 15.65		VTI1A_HUMAN (2-218): 9.83e-54: 173: 36.41
+	Dm
		1373154 Q9VV76_DROME (1-222): 8.39e-55: 176: 100.00		GOSR2_DROME (4-218): 1.17e-49: 163: 18.52
+	Hs
		151533 STX6_HUMAN (6-220): 2.18e-49: 163: 13.98		GOSR2_HUMAN (4-218): 1.04e-53: 173: 16.74
+	Hs
		212966 STX6_HUMAN (6-220): 2.18e-49: 163: 13.98		VTI1A_HUMAN (2-218): 9.83e-54: 173: 36.41
+	Hs
		1137468 Q5U8S2_HUMAN (6-211): 6.11e-49: 162: 15.39		VTI1A_HUMAN (2-218): 9.83e-54: 173: 36.41
+	Mm
		1265170 STX6_MOUSE (6-220): 2.38e-50: 166: 13.98		Q91XH6_MOUSE (2-220): 1.94e-51: 168: 23.87
+	Hs
		235222 STX10_HUMAN (6-220): 4.66e-51: 168: 15.65		VTI1B_HUMAN (2-220): 8.02e-45: 151: 22.97
+	Hs
		1284305 STX8_HUMAN (7-217): 2.73e-42: 144: 23.50		VTI1A_HUMAN (2-218): 9.83e-54: 173: 36.41
+	Hs
		151647 STX8_HUMAN (7-217): 2.73e-42: 144: 23.50		GOSR2_HUMAN (4-218): 1.04e-53: 173: 16.74
+	Hs
		213046 STX6_HUMAN (6-220): 2.18e-49: 163: 13.98		VTI1B_HUMAN (2-220): 8.02e-45: 151: 22.97
+	Hs
		1354599 STX8_HUMAN (7-217): 2.73e-42: 144: 23.50		VTI1B_HUMAN (2-220): 8.02e-45: 151: 22.97
+	Rn
		192341 BET1_RAT (147-232): 5.85e-27: 101: 15.12		GOSR2_RAT (4-218): 1.01e-54: 176: 17.67
+	Hs
		151530 BET1_HUMAN (147-232): 1.1e-25: 98.7: 13.95		GOSR2_HUMAN (4-218): 1.04e-53: 173: 16.74
+	Dm
		81377 Q9VV76_DROME (1-222): 8.39e-55: 176: 100.00		B7Z0M0_DROME (111-221): 2.07e-17: 77.1: 25.23
+	Sc
		975931 TLG1_YEAST (6-213): 2.69e-33: 121: 15.39		VTI1_YEAST (2-202): 9.42e-36: 127: 28.57
+	Sc
		701277 VAM7_YEAST (49-210): 1.34e-25: 103: 17.90		VTI1_YEAST (2-202): 9.42e-36: 127: 28.57