HitPredict

Interactor 1: DHB4 (Q9VXJ0)
Peroxisomal multifunctional enzyme type 2 (DmMFE-2) [Includes: (3R)-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.n12); Enoyl-CoA hydratase 2 (EC 4.2.1.119)]
Gene: Mfe2

Interactor 2: DHB4 (Q9VXJ0)
Peroxisomal multifunctional enzyme type 2 (DmMFE-2) [Includes: (3R)-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.n12); Enoyl-CoA hydratase 2 (EC 4.2.1.119)]
Gene: Mfe2

Species: Drosophila melanogaster

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.65 1.00 0.806

The method score is based on:

Property Details
Experiments 21320074, 23313254
Identification Methods x-ray crystallography, pull down, x ray scattering
Interaction Type association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains adh_short~adh_short, MaoC_dehydratas~MaoC_dehydratas
Common GO terms GO:0003857 - 3-hydroxyacyl-CoA dehydrogenase activity
GO:0004300 - enoyl-CoA hydratase activity
GO:0004303 - estradiol 17-beta-dehydrogenase [NAD(P)+] activity
GO:0005777 - peroxisome
GO:0006635 - fatty acid beta-oxidation
and 5 others

more...
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 598
Dm

1 598
+ Hs
+ Ce
+ Hs
+ Ss
+ Ec
+ At
+ At
+ Dm
+ At
+ Dm
+ At
+ At
+ Dm
+ At
+ At
+ At
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024