HitPredict

Interactor 1: NHR62 (O02279)
Nuclear hormone receptor family member nhr-62
Gene: nhr-62

Interactor 2: MEC3 (P09088)
Mechanosensory protein 3
Gene: mec-3

Species: Caenorhabditis elegans

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.43	0.60	0.508

Property	Details
Experiments	23791784
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0006355 - regulation of DNA-templated transcription
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 515 Ce			1 321
+	Ce
		106954 NH114_CAEEL (84-511): 8.12e-100: 308: 19.31		MEC3_CAEEL (1-321): 1.79e-71: 226: 100.00
+	Hs
		823708 NR2C2_HUMAN (34-511): 7.04e-97: 306: 14.34		LHX2_HUMAN (6-311): 4.03e-63: 207: 21.86
+	Ce
		109948 H2KZU3_CAEEL (73-504): 1.52e-87: 277: 33.26		MEC3_CAEEL (1-321): 1.79e-71: 226: 100.00
+	Ce
		109972 H2KZU4_CAEEL (73-504): 4.85e-87: 276: 32.30		MEC3_CAEEL (1-321): 1.79e-71: 226: 100.00
+	Ce
		106955 NH114_CAEEL (84-511): 8.12e-100: 308: 19.31		LIN11_CAEEL (10-289): 2.15e-53: 181: 32.51
+	Hs
		369297 ESR1_HUMAN (22-513): 1.55e-101: 319: 15.63		ISL1_HUMAN (27-288): 1.71e-48: 167: 24.15
+	Hs
		490094 COT1_HUMAN (30-515): 1.9e-100: 310: 17.70		ISL1_HUMAN (27-288): 1.71e-48: 167: 24.15
+	Ce
		447563 Q86PI8_CAEEL (86-371): 2.93e-77: 246: 22.87		MEC3_CAEEL (1-321): 1.79e-71: 226: 100.00
+	Hs
		369306 ESR1_HUMAN (22-513): 1.55e-101: 319: 15.63		LMO4_HUMAN (10-165): 3.44e-39: 137: 18.75
+	Ce
		590583 NHR31_CAEEL (59-489): 7.13e-83: 270: 23.06		HM14_CAEEL (18-289): 5.37e-56: 186: 28.31
+	Hs
		369176 ESR1_HUMAN (22-513): 1.55e-101: 319: 15.63		PAXI_HUMAN (2-208): 2.41e-31: 125: 15.79
+	Ce
		104766 H2KZU3_CAEEL (73-504): 1.52e-87: 277: 33.26		LIM7_CAEEL (16-288): 3.64e-46: 163: 23.73
+	Ce
		104767 H2KZU4_CAEEL (73-504): 4.85e-87: 276: 32.30		LIM7_CAEEL (16-288): 3.64e-46: 163: 23.73
+	Hs
		782510 HNF4A_HUMAN (45-510): 2.94e-85: 272: 19.74		ISL1_HUMAN (27-288): 1.71e-48: 167: 24.15
+	Ce
		589697 Q86PI8_CAEEL (86-371): 2.93e-77: 246: 22.87		LIN11_CAEEL (10-289): 2.15e-53: 181: 32.51
+	Hs
		740488 PPARG_HUMAN (31-505): 1.99e-74: 245: 19.36		LMO4_HUMAN (10-165): 3.44e-39: 137: 18.75
+	Hs
		824253 NR2C2_HUMAN (34-511): 7.04e-97: 306: 14.34		LHX4_HUMAN (3-81): 1.14e-10: 63.8: 22.89
+	Hs
		824492 NR2C2_HUMAN (34-511): 7.04e-97: 306: 14.34		LHX3_HUMAN (3-81): 2.49e-09: 60: 20.48
+	Ce
		447549 Q21372_CAEEL (98-319): 1.05e-26: 114: 33.18		MEC3_CAEEL (1-321): 1.79e-71: 226: 100.00
+	Hs
		525296 NR2C1_HUMAN (97-212): 5.96e-23: 104: 44.26		LHX2_HUMAN (6-311): 4.03e-63: 207: 21.86