HitPredict - High confidence protein-protein interactions

Interactor 1: Q9W3I9 (Q9W3I9)
GH01161p (TNF-receptor-associated factor 6)
Gene: Traf6

Interactor 2: Q9W3I9 (Q9W3I9)
GH01161p (TNF-receptor-associated factor 6)
Gene: Traf6

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.59	0.60	0.595

Property	Details
Experiments	10021364, 14605208
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000209 - protein polyubiquitination GO:0005164 - tumor necrosis factor receptor binding GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0007391 - dorsal closure and 18 others more... GO:0008270 - zinc ion binding GO:0010508 - positive regulation of autophagy GO:0031663 - lipopolysaccharide-mediated signaling pathway GO:0032813 - tumor necrosis factor receptor superfamily binding GO:0033209 - tumor necrosis factor-mediated signaling pathway GO:0043068 - positive regulation of programmed cell death GO:0043122 - regulation of canonical NF-kappaB signal transduction GO:0043123 - positive regulation of canonical NF-kappaB signal transduction GO:0045087 - innate immune response GO:0045746 - negative regulation of Notch signaling pathway GO:0045752 - positive regulation of Toll signaling pathway GO:0046330 - positive regulation of JNK cascade GO:0050688 - regulation of defense response to virus GO:0060255 - regulation of macromolecule metabolic process GO:0061059 - positive regulation of peptidoglycan recognition protein signaling pathway GO:0061630 - ubiquitin protein ligase activity GO:0070534 - protein K63-linked ubiquitination GO:1903265 - positive regulation of tumor necrosis factor-mediated signaling pathway
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1	475
Dm

1	475

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Last updated: 15 Jul 2024