Interactor 1: CHIP (Q9WUD1)
E3 ubiquitin-protein ligase CHIP (EC 2.3.2.27) (Carboxy terminus of Hsp70-interacting protein) (RING-type E3 ubiquitin transferase CHIP) (STIP1 homology and U box-containing protein 1)
Gene: Stub1

Interactor 2: CHIP (Q9WUD1)
E3 ubiquitin-protein ligase CHIP (EC 2.3.2.27) (Carboxy terminus of Hsp70-interacting protein) (RING-type E3 ubiquitin transferase CHIP) (STIP1 homology and U box-containing protein 1)
Gene: Stub1

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.77 1.00 0.882

The method score is based on:

Property Details
Experiments 16307917, 11435423, 26206088, 31951392
Identification Methods x-ray crystallography, enzymatic study
Interaction Type association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains ANAPC3~ANAPC3, ANAPC3~CHIP_TPR_N, CHIP_TPR_N~CHIP_TPR_N, CHIP_TPR_N~U-box, U-box~U-box
Common GO terms GO:0000151 - ubiquitin ligase complex
GO:0000165 - MAPK cascade
GO:0000209 - protein polyubiquitination
GO:0001664 - G protein-coupled receptor binding
GO:0002931 - response to ischemia
and 53 others

more...

Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 304
Mm

1 304
+ Hs
+ Ce
+ Dm
+ Mm
+ Mm
+ Hs
+ Ps
+ Mm
+ Rn
+ Dm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024