HitPredict

Interactor 1: SHAN1 (Q9WV48)
SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (GKAP/SAPAP-interacting protein) (SPANK-1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP) (Synamon)
Gene: Shank1

Interactor 2: HOME1 (Q9Z214)
Homer protein homolog 1 (PSD-Zip45) (VASP/Ena-related gene up-regulated during seizure and LTP 1) (Vesl-1)
Gene: Homer1

Species: Rattus norvegicus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.71 0.60 0.653

The method score is based on:

Property Details
Experiments 10433269, 19345194
Identification Methods two hybrid, pull down, affinity chromatography technology, cosedimentation in solution, light scattering, electron microscopy
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0014069 - postsynaptic density
GO:0016020 - membrane
GO:0030425 - dendrite
and 6 others

more...
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 2167
Rn

1 366
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024