Interactor 1: FTSH (Q9WZ49)
ATP-dependent zinc metalloprotease FtsH (EC 3.4.24.-)
Gene: FTSH

Interactor 2: FTSH (Q9WZ49)
ATP-dependent zinc metalloprotease FtsH (EC 3.4.24.-)
Gene: FTSH

Species: Thermotoga maritima MSB8

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.67 1.00 0.820

The method score is based on:

Property Details
Experiments 19955424, 16484367
Identification Methods x-ray crystallography, molecular sieving, cosedimentation in solution
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains AAA~AAA, AAA~AAA_lid_3, AAA~Peptidase_M41, AAA_lid_3~AAA_lid_3, AAA_lid_3~Peptidase_M41, FtsH_ext~FtsH_ext, Peptidase_M41~Peptidase_M41
Common GO terms GO:0004176 - ATP-dependent peptidase activity
GO:0004222 - metalloendopeptidase activity
GO:0005524 - ATP binding
GO:0005886 - plasma membrane
GO:0006508 - proteolysis
and 3 others

more...

Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 610
Tm

1 610
+ At
+ Pf
+ At
+ Sc
+ At
+ Dm
+ At
+ Rn
+ Hs
+ Mm
+ Ce
+ Ec
+ At
+ At
+ Sc
+ At

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024