Interactor 1: MCM7 (Q9XYU0)
DNA replication licensing factor Mcm7 (EC 3.6.4.12) (Minichromosome maintenance 7 protein) (DmMCM3)
Gene: MCM7

Interactor 2: MCM3 (Q9XYU1)
DNA replication licensing factor Mcm3 (EC 3.6.4.12) (Minichromosome maintenance 3 protein) (DmMCM3)
Gene: MCM3

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.68 1.00 0.827

The method score is based on:

Property Details
Experiments 25117490, 22036573, 21378962
Identification Methods pull down, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains MCM~MCM, MCM~MCM_lid, MCM~MCM_N, MCM~MCM_OB, MCM_N~MCM_N, MCM_N~MCM_OB, MCM_OB~MCM_OB
Common GO terms GO:0000727 - double-strand break repair via break-induced replication
GO:0003697 - single-stranded DNA binding
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0006271 - DNA strand elongation involved in DNA replication
and 5 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 720
Dm

1 819
+ Mm
+ Hs
+ Xl
+ Hs
+ Xl
+ Hs
+ Ce
+ Xl
+ Hs
+ Hs
+ Xl
+ Sp
+ Xl
+ Dm
+ Dm
+ Hs
+ Dm
+ Xl
+ At
+ Sp

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Last updated: 15 Jul 2024