Interactor 1: NOD1 (Q9Y239)
Nucleotide-binding oligomerization domain-containing protein 1 (hNod1) (Caspase recruitment domain-containing protein 4)
Gene: NOD1

Interactor 2: NOD1 (Q9Y239)
Nucleotide-binding oligomerization domain-containing protein 1 (hNod1) (Caspase recruitment domain-containing protein 4)
Gene: NOD1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.74 1.00 0.861

The method score is based on:

Property Details
Experiments 23300079, 10329646, 18186648
Identification Methods pull down, affinity chromatography technology, x-ray crystallography, molecular sieving
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains CARD~CARD, LRR_6~LRR_6, NACHT~NACHT, NACHT~NLRC4_HD2, NACHT~NOD2_WH, NLRC4_HD2~NOD2_WH
Common GO terms GO:0002221 - pattern recognition receptor signaling pathway
GO:0002606 - positive regulation of dendritic cell antigen processing and presentation
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0005829 - cytosol
and 44 others

more...

Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 953
Hs

1 953
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024