HitPredict

Interactor 1: AKT3 (Q9Y243)
RAC-gamma serine/threonine-protein kinase (EC 2.7.11.1) (Protein kinase Akt-3) (Protein kinase B gamma) (PKB gamma) (RAC-PK-gamma) (STK-2)
Gene: AKT3

Interactor 2: SNX8 (Q9Y5X2)
Sorting nexin-8
Gene: SNX8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.80	0.726

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	PH~PX
Common GO terms	-
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 479 Hs			1 465
+	Rn
		1144335 AKT3_RAT (1-479): 0: 577: 99.17		SNX1_RAT (5-443): 9.63e-83: 266: 16.88
+	Hs
		682200 AKT2_HUMAN (1-479): 0: 561: 75.78		SNX27_HUMAN (3-422): 1.85e-72: 240: 12.86
+	Hs
		1073467 KS6A1_HUMAN (54-459): 5.85e-103: 325: 21.91		SNX27_HUMAN (3-422): 1.85e-72: 240: 12.86
+	Hs
		850702 KS6A3_HUMAN (146-418): 7.07e-101: 320: 28.52		SNX27_HUMAN (3-422): 1.85e-72: 240: 12.86