HitPredict

Interactor 1: RUVB1 (Q9Y265)
RuvB-like 1 (EC 3.6.4.12) (49 kDa TATA box-binding protein-interacting protein) (49 kDa TBP-interacting protein) (54 kDa erythrocyte cytosolic protein) (ECP-54) (INO80 complex subunit H) (Nuclear matrix protein 238) (NMP 238) (Pontin 52) (TIP49a) (TIP60-associated protein 54-alpha) (TAP54-alpha)
Gene: RUVBL1

Interactor 2: TRRAP (Q9Y4A5)
Transformation/transcription domain-associated protein (350/400 kDa PCAF-associated factor) (PAF350/400) (STAF40) (Tra1 homolog)
Gene: TRRAP

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.90 0.60 0.738

The method score is based on:

Property Details
Experiments 26496610, 35271311, 28514442, 11839798, 33961781, 20371770
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, pull down
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000786 - nucleosome
GO:0000812 - Swr1 complex
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006281 - DNA repair
and 9 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 456
Hs

1 3859
+ Hs
+ Dm
+ Sc
+ Mm
+ Sp
+ Sp
+ Hs
+ Dm
+ Hs
+ Dm
+ Sc
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Sc
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024