HitPredict

Interactor 1: RUVB1 (Q9Y265)
RuvB-like 1 (EC 3.6.4.12) (49 kDa TATA box-binding protein-interacting protein) (49 kDa TBP-interacting protein) (54 kDa erythrocyte cytosolic protein) (ECP-54) (INO80 complex subunit H) (Nuclear matrix protein 238) (NMP 238) (Pontin 52) (TIP49a) (TIP60-associated protein 54-alpha) (TAP54-alpha)
Gene: RUVBL1

Interactor 2: TRAF6 (Q9Y4K3)
TNF receptor-associated factor 6 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF6) (Interleukin-1 signal transducer) (RING finger protein 85) (RING-type E3 ubiquitin transferase TRAF6)
Gene: TRAF6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	17353931
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0042981 - regulation of apoptotic process
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 456 Hs			1 522
+	Hs
		1376986 RUVB2_HUMAN (2-455): 0: 651: 42.76		TRAF6_HUMAN (1-522): 1.12e-151: 445: 100.00
+	Hs
		1020993 RUVB1_HUMAN (1-456): 0: 704: 100.00		TRAF2_HUMAN (40-500): 7.2e-101: 314: 25.85
+	Hs
		1020990 RUVB2_HUMAN (2-455): 0: 651: 42.76		TRAF2_HUMAN (40-500): 7.2e-101: 314: 25.85
+	Hs
		1252556 RUVB2_HUMAN (2-455): 0: 651: 42.76		LNX1_HUMAN (58-183): 2.59e-11: 68.3: 19.84