HitPredict

Interactor 1: FBW1A (Q9Y297)
F-box/WD repeat-containing protein 1A (E3RSIkappaB) (Epididymis tissue protein Li 2a) (F-box and WD repeats protein beta-TrCP) (pIkappaBalpha-E3 receptor subunit)
Gene: BTRC

Interactor 2: RPGF2 (Q9Y4G8)
Rap guanine nucleotide exchange factor 2 (Cyclic nucleotide ras GEF) (CNrasGEF) (Neural RAP guanine nucleotide exchange protein) (nRap GEP) (PDZ domain-containing guanine nucleotide exchange factor 1) (PDZ-GEF1) (RA-GEF-1) (Ras/Rap1-associating GEF-1)
Gene: RAPGEF2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	25332235, 26091241, 25515538
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 605 Hs			1 1499
+	Hs
		1356381 FBW1B_HUMAN (96-605): 1.89e-143: 428: 85.69		RPGF2_HUMAN (1-1499): 0: 1710: 100.00
+	Hs
		1047055 FBW1A_HUMAN (1-605): 0: 551: 100.00		RPGF1_HUMAN (497-962): 7.1e-99: 345: 19.96
+	Hs
		1047054 FBW1B_HUMAN (96-605): 1.89e-143: 428: 85.69		RPGF1_HUMAN (497-962): 7.1e-99: 345: 19.96