Interactor 1: TLR6 (Q9Y2C9)
Toll-like receptor 6 (CD antigen CD286)
Gene: TLR6

Interactor 2: TLR6 (Q9Y2C9)
Toll-like receptor 6 (CD antigen CD286)
Gene: TLR6

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.46 1.00 0.683

The method score is based on:

Property Details
Experiments 23155421
Identification Methods tox-r dimerization assay, fluorescence technology, cosedimentation in solution
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains LRR_8~LRR_8, LRR_8~LRRCT, TIR~TIR
Common GO terms GO:0001540 - amyloid-beta binding
GO:0001774 - microglial cell activation
GO:0002224 - toll-like receptor signaling pathway
GO:0002755 - MyD88-dependent toll-like receptor signaling pathway
GO:0004888 - transmembrane signaling receptor activity
and 38 others

more...

Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 796
Hs

1 796
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+ At
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+ Mm
+ At
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+ Dm
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024