HitPredict

Interactor 1: GIT1 (Q9Y2X7)
ARF GTPase-activating protein GIT1 (ARF GAP GIT1) (Cool-associated and tyrosine-phosphorylated protein 1) (CAT-1) (CAT1) (G protein-coupled receptor kinase-interactor 1) (GRK-interacting protein 1) (p95-APP1)
Gene: GIT1

Interactor 2: GIT1 (Q9Y2X7)
ARF GTPase-activating protein GIT1 (ARF GAP GIT1) (Cool-associated and tyrosine-phosphorylated protein 1) (CAT-1) (CAT1) (G protein-coupled receptor kinase-interactor 1) (GRK-interacting protein 1) (p95-APP1)
Gene: GIT1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.76 1.00 0.873

The method score is based on:

Property Details
Experiments 17898078, 25742295, 12473661
Identification Methods affinity chromatography technology, pull down, two hybrid
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Ank_2~Ank_2, Ank_2~ArfGap, Ank_2~GIT_SHD, ArfGap~ArfGap, ArfGap~GIT_SHD, GIT1_C~GIT1_C, GIT_CC~GIT_CC, GIT_SHD~GIT_SHD
Common GO terms GO:0001957 - intramembranous ossification
GO:0005096 - GTPase activator activity
GO:0005739 - mitochondrion
GO:0005813 - centrosome
GO:0005829 - cytosol
and 30 others

more...
Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 761
Hs

1 761
+ Rn
+ Hs
+ Gg
+ Hs
+ Mm
+ Mm
+ Mm
+ Mm
+ Hs
+ Hs
+ Hs
+ At
+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024