HitPredict

Interactor 1: UB2D4 (Q9Y2X8)
Ubiquitin-conjugating enzyme E2 D4 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme D4) (HBUCE1) (Ubiquitin carrier protein D4) (Ubiquitin-protein ligase D4)
Gene: UBE2D4

Interactor 2: RNF11 (Q9Y3C5)
RING finger protein 11
Gene: RNF11

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.93	1.00	0.965

Property	Details
Experiments	32296183, 19690564, 19549727, 21516116, 15231748, 31515488, unassigned1304
Identification Methods	two hybrid, two hybrid array, two hybrid prey pooling approach, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	UQ_con~zf-RING_2
Common GO terms	GO:0000151 - ubiquitin ligase complex GO:0005634 - nucleus GO:0006511 - ubiquitin-dependent protein catabolic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 147 Hs			1 154
+	Hs
		849494 UB2D1_HUMAN (1-147): 4.61e-83: 241: 91.84		RNF11_HUMAN (1-154): 1.51e-42: 140: 100.00
+	Hs
		207572 UB2D4_HUMAN (1-147): 8.89e-84: 243: 100.00		RNF13_HUMAN (77-146): 1.55e-26: 104: 33.80
+	Hs
		1377467 UB2D4_HUMAN (1-147): 8.89e-84: 243: 100.00		RN115_HUMAN (10-154): 2e-26: 102: 19.08
+	Hs
		207545 UB2D1_HUMAN (1-147): 4.61e-83: 241: 91.84		RNF13_HUMAN (77-146): 1.55e-26: 104: 33.80
+	At
		715137 UBC9_ARATH (1-147): 1.26e-82: 241: 80.27		RNG1L_ARATH (15-153): 5.68e-27: 104: 23.61
+	Hs
		1204871 UB2D4_HUMAN (1-147): 8.89e-84: 243: 100.00		GOLI_HUMAN (57-146): 1.98e-25: 101: 24.44
+	Zm
		74334 B4FC97_MAIZE (1-147): 1.78e-83: 243: 79.59		B6U926_MAIZE (52-153): 2.57e-25: 101: 29.52
+	Zm
		79637 B6SZE0_MAIZE (1-147): 1.8e-83: 243: 79.59		B6U926_MAIZE (52-153): 2.57e-25: 101: 29.52
+	Hs
		849497 UB2D1_HUMAN (1-147): 4.61e-83: 241: 91.84		RN115_HUMAN (10-154): 2e-26: 102: 19.08
+	Hs
		849359 UB2D1_HUMAN (1-147): 4.61e-83: 241: 91.84		GOLI_HUMAN (57-146): 1.98e-25: 101: 24.44
+	Hs
		1356934 UB2D4_HUMAN (1-147): 8.89e-84: 243: 100.00		RN150_HUMAN (57-146): 3.61e-24: 98.4: 26.67
+	Hs
		849382 UB2D1_HUMAN (1-147): 4.61e-83: 241: 91.84		RN128_HUMAN (57-153): 7.46e-25: 100: 25.77
+	Hs
		849491 UB2D1_HUMAN (1-147): 4.61e-83: 241: 91.84		RNF6_HUMAN (1-149): 3.51e-24: 99.2: 20.83
+	Hs
		849485 UB2D1_HUMAN (1-147): 4.61e-83: 241: 91.84		RN150_HUMAN (57-146): 3.61e-24: 98.4: 26.67
+	At
		715139 UBC9_ARATH (1-147): 1.26e-82: 241: 80.27		RHG1A_ARATH (13-141): 1.35e-23: 97.6: 14.93
+	At
		715158 UBC11_ARATH (1-147): 8.34e-83: 241: 79.59		RHG1A_ARATH (13-141): 1.35e-23: 97.6: 14.93
+	Hs
		1346940 UB2D4_HUMAN (1-147): 8.89e-84: 243: 100.00		RNF12_HUMAN (91-146): 1.14e-21: 91.8: 39.29
+	Hs
		849459 UB2D1_HUMAN (1-147): 4.61e-83: 241: 91.84		RNF12_HUMAN (91-146): 1.14e-21: 91.8: 39.29
+	Hs
		1332598 UB2D4_HUMAN (1-147): 8.89e-84: 243: 100.00		RN167_HUMAN (77-143): 4.96e-21: 89.1: 36.77
+	Hs
		849446 UB2D1_HUMAN (1-147): 4.61e-83: 241: 91.84		RN167_HUMAN (77-143): 4.96e-21: 89.1: 36.77