HitPredict

Interactor 1: DHRS7 (Q9Y394)
Dehydrogenase/reductase SDR family member 7 (EC 1.1.1.-) (Retinal short-chain dehydrogenase/reductase 4) (retSDR4) (Short chain dehydrogenase/reductase family 34C member 1) (Protein SDR34C1)
Gene: DHRS7

Interactor 2: SRPRB (Q9Y5M8)
Signal recognition particle receptor subunit beta (SR-beta) (Protein APMCF1)
Gene: SRPRB

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005789 - endoplasmic reticulum membrane GO:0016020 - membrane
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 339 Hs			1 271
+	Hs
		950747 DHRS7_HUMAN (1-339): 3.04e-101: 303: 100.00		ARF5_HUMAN (46-240): 5.42e-75: 227: 21.03
+	Hs
		950658 DHB11_HUMAN (43-311): 2.07e-68: 217: 27.31		ARF5_HUMAN (46-240): 5.42e-75: 227: 21.03
+	Hs
		1253261 RDH11_HUMAN (42-300): 2.53e-68: 218: 25.09		SRPRB_HUMAN (1-271): 4.47e-69: 216: 100.00
+	Hs
		1240375 DHB11_HUMAN (43-311): 2.07e-68: 217: 27.31		SRPRB_HUMAN (1-271): 4.47e-69: 216: 100.00
+	Dm
		52010 A1Z729_DROME (12-311): 2.43e-67: 216: 19.75		O18332_DROME (54-264): 1.27e-62: 197: 15.02
+	Dm
		52033 A1Z729_DROME (12-311): 2.43e-67: 216: 19.75		ARF1_DROME (46-239): 1.12e-62: 196: 22.17
+	Hs
		950524 DHB11_HUMAN (43-311): 2.07e-68: 217: 27.31		ARF1_HUMAN (46-240): 2.73e-62: 195: 21.54