HitPredict

Interactor 1: CHMP3 (Q9Y3E7)
Charged multivesicular body protein 3 (Chromatin-modifying protein 3) (Neuroendocrine differentiation factor) (Vacuolar protein sorting-associated protein 24) (hVps24)
Gene: CHMP3

Interactor 2: TNPO3 (Q9Y5L0)
Transportin-3 (Importin-12) (Imp12) (Transportin-SR) (TRN-SR)
Gene: TNPO3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.43	0.50	0.464

Property	Details
Experiments	16730941
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 222 Hs			1 923
+	Hs
		208874 CHM2A_HUMAN (7-221): 5.79e-45: 151: 24.19		TNPO3_HUMAN (1-923): 0: 657: 100.00
+	Hs
		1185558 CHM1B_HUMAN (23-222): 6.07e-34: 122: 17.00		TNPO3_HUMAN (1-923): 0: 657: 100.00
+	Hs
		1316090 CHM4A_HUMAN (3-208): 3.21e-15: 73.6: 16.29		TNPO3_HUMAN (1-923): 0: 657: 100.00
+	Hs
		162230 CHM2A_HUMAN (7-221): 5.79e-45: 151: 24.19		XPO1_HUMAN (3-920): 6.76e-151: 475: 12.37
+	Hs
		163483 CHM2B_HUMAN (8-208): 4.24e-43: 146: 25.87		XPO1_HUMAN (3-920): 6.76e-151: 475: 12.37
+	Xl
		1146029 CH2BB_XENLA (8-213): 2.14e-43: 146: 26.70		Q6NS03_XENLA (3-918): 4.57e-148: 467: 12.80
+	Hs
		163111 CHM4C_HUMAN (10-215): 2.19e-10: 60.1: 14.82		XPO1_HUMAN (3-920): 6.76e-151: 475: 12.37
+	Xl
		1151517 CHM4C_XENLA (35-215): 1.15e-10: 60.9: 15.76		Q6NS03_XENLA (3-918): 4.57e-148: 467: 12.80
+	Hs
		312387 CHM4B_HUMAN (10-208): 2.44e-13: 68.2: 17.31		IPO7_HUMAN (13-813): 8.63e-101: 340: 11.63
+	Hs
		312353 CHM4C_HUMAN (10-215): 2.19e-10: 60.1: 14.82		IPO7_HUMAN (13-813): 8.63e-101: 340: 11.63
+	Hs
		127370 CHM4B_HUMAN (10-208): 2.44e-13: 68.2: 17.31		IPO5_HUMAN (68-703): 1.92e-86: 301: 13.24