HitPredict

Interactor 1: SAMH1 (Q9Y3Z3)
Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 (dNTPase) (EC 3.1.5.-) (Dendritic cell-derived IFNG-induced protein) (DCIP) (Monocyte protein 5) (MOP-5) (SAM domain and HD domain-containing protein 1) (hSAMHD1)
Gene: SAMHD1

Interactor 2: DCAF1 (Q9Y4B6)
DDB1- and CUL4-associated factor 1 (HIV-1 Vpr-binding protein) (VprBP) (Serine/threonine-protein kinase VPRBP) (EC 2.7.11.1) (Vpr-interacting protein)
Gene: DCAF1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.79	0.60	0.692

Property	Details
Experiments	23677995, 24336198, 35803902, 22362772
Identification Methods	enzymatic study, x-ray crystallography, pull down, affinity chromatography technology
Interaction Type	direct interaction, association, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	1

Homologous interactions

Color coding for hit scores

	1 626 Hs			1 1507
+	Hs
		1281507 SAMH1_HUMAN (1-626): 0: 965: 100.00		FBXW7_HUMAN (1039-1242): 6.77e-37: 152: 9.64