HitPredict - High confidence protein-protein interactions

Interactor 1: PLXD1 (Q9Y4D7)
Plexin-D1
Gene: PLXND1

Interactor 2: PLXD1 (Q9Y4D7)
Plexin-D1
Gene: PLXND1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Interacting Pfam domains	Plexin_cytopl~Plexin_cytopl, Plexin_RBD~Plexin_RBD, PSI~Sema, PSI~TIG, PSI~TIG_plexin, Sema~Sema, Sema~TIG, Sema~TIG_plexin, TIG~TIG, TIG_plexin~TIG_plexin
Common GO terms	GO:0001525 - angiogenesis GO:0001569 - branching involved in blood vessel morphogenesis GO:0001822 - kidney development GO:0002116 - semaphorin receptor complex GO:0003151 - outflow tract morphogenesis and 23 others more... GO:0003279 - cardiac septum development GO:0005886 - plasma membrane GO:0007162 - negative regulation of cell adhesion GO:0007416 - synapse assembly GO:0008039 - synaptic target recognition GO:0008360 - regulation of cell shape GO:0017154 - semaphorin receptor activity GO:0019904 - protein domain specific binding GO:0030027 - lamellipodium GO:0030334 - regulation of cell migration GO:0030424 - axon GO:0031258 - lamellipodium membrane GO:0035904 - aorta development GO:0043524 - negative regulation of neuron apoptotic process GO:0043542 - endothelial cell migration GO:0044297 - cell body GO:0045765 - regulation of angiogenesis GO:0050772 - positive regulation of axonogenesis GO:0060666 - dichotomous subdivision of terminal units involved in salivary gland branching GO:0060976 - coronary vasculature development GO:0071526 - semaphorin-plexin signaling pathway GO:0098978 - glutamatergic synapse GO:1902287 - semaphorin-plexin signaling pathway involved in axon guidance
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1	1925
Hs

1	1925

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024