HitPredict

Interactor 1: UBP15 (Q9Y4E8)
Ubiquitin carboxyl-terminal hydrolase 15 (EC 3.4.19.12) (Deubiquitinating enzyme 15) (Ubiquitin thioesterase 15) (Ubiquitin-specific-processing protease 15) (Unph-2) (Unph4)
Gene: USP15

Interactor 2: UBP15 (Q9Y4E8)
Ubiquitin carboxyl-terminal hydrolase 15 (EC 3.4.19.12) (Deubiquitinating enzyme 15) (Ubiquitin thioesterase 15) (Ubiquitin-specific-processing protease 15) (Unph-2) (Unph4)
Gene: USP15

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.76 1.00 0.875

The method score is based on:

Property Details
Experiments 32671073, 33378683, 22001210
Identification Methods affinity chromatography technology, x-ray crystallography, pull down, molecular sieving, x ray scattering
Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains DUSP~DUSP, DUSP~Ubiquitin_3, Ubiquitin_3~Ubiquitin_3, UCH~UCH, UCH~USP7_C2, USP7_C2~USP7_C2
Common GO terms GO:0004197 - cysteine-type endopeptidase activity
GO:0004843 - cysteine-type deubiquitinase activity
GO:0005160 - transforming growth factor beta receptor binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
and 19 others

more...
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 981
Hs

1 981
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024