Interactor 1: TRAF6 (Q9Y4K3)
TNF receptor-associated factor 6 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF6) (Interleukin-1 signal transducer) (RING finger protein 85) (RING-type E3 ubiquitin transferase TRAF6)
Gene: TRAF6

Interactor 2: TRAF6 (Q9Y4K3)
TNF receptor-associated factor 6 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF6) (Interleukin-1 signal transducer) (RING finger protein 85) (RING-type E3 ubiquitin transferase TRAF6)
Gene: TRAF6

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.99 1.00 0.995

The method score is based on:

Property Details
Experiments 15125833, 19549727, 25340740, 25416956, 21185369, 25527291, 25425640, 25642822, 28214532, 27791197, 27501752, 27586056, 27918549, 28522566, 28244869, 28884970, 29176576, 27107012, 30996248, 30929559 and 21 others

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Identification Methods enzymatic study, two hybrid, pull down, affinity chromatography technology, fluorescent resonance energy transfer, anti tag coimmunoprecipitation, two hybrid array, barcode fusion genetics two hybrid, validated two hybrid, molecular sieving and 3 others

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Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains zf-C3HC4_2~zf-C3HC4_2
Common GO terms GO:0000045 - autophagosome assembly
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000209 - protein polyubiquitination
GO:0001503 - ossification
GO:0001701 - in utero embryonic development
and 73 others

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Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 522
Hs

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Last updated: 15 Jul 2024