HitPredict

Interactor 1: TRAF6 (Q9Y4K3)
TNF receptor-associated factor 6 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF6) (Interleukin-1 signal transducer) (RING finger protein 85) (RING-type E3 ubiquitin transferase TRAF6)
Gene: TRAF6

Interactor 2: HYOU1 (Q9Y4L1)
Hypoxia up-regulated protein 1 (150 kDa oxygen-regulated protein) (ORP-150) (170 kDa glucose-regulated protein) (GRP-170) (Heat shock protein family H member 4)
Gene: HYOU1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	17353931
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 522 Hs			1 999
+	Hs
		320933 TRAF6_HUMAN (1-522): 1.12e-151: 445: 100.00		HS74L_HUMAN (33-960): 0: 793: 24.57
+	Hs
		714476 TRAF6_HUMAN (1-522): 1.12e-151: 445: 100.00		HSP74_HUMAN (33-964): 0: 785: 25.64
+	Hs
		714201 TRAF2_HUMAN (40-500): 7.2e-101: 314: 25.85		HSP74_HUMAN (33-964): 0: 785: 25.64
+	Hs
		714101 TRAF6_HUMAN (1-522): 1.12e-151: 445: 100.00		HS71L_HUMAN (682-814): 9.92e-31: 131: 15.04
+	Hs
		505009 TRAF6_HUMAN (1-522): 1.12e-151: 445: 100.00		HSP7C_HUMAN (682-815): 2.07e-30: 130: 16.42
+	Mm
		926117 TRAF6_MOUSE (1-522): 5.7e-141: 418: 87.93		HSP7C_MOUSE (682-815): 1.96e-30: 130: 16.42
+	Mm
		565424 TRAF6_MOUSE (1-522): 5.7e-141: 418: 87.93		HSP72_MOUSE (682-814): 2.4e-29: 126: 15.79
+	Mm
		571853 TRAF6_MOUSE (1-522): 5.7e-141: 418: 87.93		HS71B_MOUSE (682-813): 1.49e-28: 124: 15.91
+	Hs
		713952 TRAF2_HUMAN (40-500): 7.2e-101: 314: 25.85		HS71L_HUMAN (682-814): 9.92e-31: 131: 15.04
+	Hs
		503989 TRAF2_HUMAN (40-500): 7.2e-101: 314: 25.85		HSP7C_HUMAN (682-815): 2.07e-30: 130: 16.42
+	Hs
		713954 TRAF1_HUMAN (50-501): 5.58e-64: 216: 19.40		HS71L_HUMAN (682-814): 9.92e-31: 131: 15.04
+	Hs
		503998 TRAF1_HUMAN (50-501): 5.58e-64: 216: 19.40		HSP7C_HUMAN (682-815): 2.07e-30: 130: 16.42
+	Hs
		713970 TRI25_HUMAN (63-370): 4.93e-45: 169: 18.61		HS71L_HUMAN (682-814): 9.92e-31: 131: 15.04
+	Hs
		504072 TRI25_HUMAN (63-370): 4.93e-45: 169: 18.61		HSP7C_HUMAN (682-815): 2.07e-30: 130: 16.42
+	Hs
		871567 TRI25_HUMAN (63-370): 4.93e-45: 169: 18.61		HSP72_HUMAN (682-814): 8.57e-30: 128: 16.54
+	Hs
		301573 TRI37_HUMAN (56-501): 7.36e-43: 165: 13.89		HSP7C_HUMAN (682-815): 2.07e-30: 130: 16.42
+	Hs
		563999 RO52_HUMAN (64-403): 5.77e-45: 166: 14.97		HSP76_HUMAN (682-813): 1.1e-27: 121: 19.70
+	Hs
		1120600 TRI17_HUMAN (58-408): 7.59e-43: 160: 11.86		Q53FC7_HUMAN (682-813): 3.1e-27: 120: 20.46
+	Hs
		504715 TRIM6_HUMAN (56-403): 5.03e-39: 150: 12.97		HSP7C_HUMAN (682-815): 2.07e-30: 130: 16.42
+	Hs
		503987 TRI26_HUMAN (61-410): 2.85e-38: 149: 14.59		HSP7C_HUMAN (682-815): 2.07e-30: 130: 16.42