HitPredict

Interactor 1: RN114 (Q9Y508)
E3 ubiquitin-protein ligase RNF114 (EC 2.3.2.27) (RING finger protein 114) (RING-type E3 ubiquitin transferase RNF114) (Zinc finger protein 228) (Zinc finger protein 313)
Gene: RNF114

Interactor 2: RN114 (Q9Y508)
E3 ubiquitin-protein ligase RNF114 (EC 2.3.2.27) (RING finger protein 114) (RING-type E3 ubiquitin transferase RNF114) (Zinc finger protein 228) (Zinc finger protein 313)
Gene: RNF114

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.71 1.00 0.845

The method score is based on:

Property Details
Experiments 21571784, 31209351, 23645206
Identification Methods enzymatic study
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains zf-RING_UBOX~zf-RING_UBOX, zf_C2HC_14~zf_C2HC_14
Common GO terms GO:0000209 - protein polyubiquitination
GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0006511 - ubiquitin-dependent protein catabolic process
and 4 others

more...
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 228
Hs

1 228
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+ Mm
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024