HitPredict

Interactor 1: SHAN1 (Q9Y566)
SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP)
Gene: SHANK1

Interactor 2: SHAN1 (Q9Y566)
SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP)
Gene: SHANK1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.62 1.00 0.793

The method score is based on:

Property Details
Experiments 12954649, 23897824
Identification Methods x-ray crystallography, two hybrid, affinity chromatography technology
Interaction Type association, direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Ank_2~Ank_2, PDZ_6~PDZ_6, SAM_1~SAM_1, SH3_2~SH3_2
Common GO terms GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0007616 - long-term memory
GO:0008306 - associative learning
GO:0014069 - postsynaptic density
and 32 others

more...
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 2161
Hs

1 2161
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Last updated: 15 Jul 2024