HitPredict

Interactor 1: PCDB6 (Q9Y5E3)
Protocadherin beta-6 (PCDH-beta-6)
Gene: PCDHB6

Interactor 2: PCDBC (Q9Y5F1)
Protocadherin beta-12 (PCDH-beta-12)
Gene: PCDHB12

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Cadherin~Cadherin, Cadherin~Cadherin_2
Common GO terms	GO:0005509 - calcium ion binding GO:0005886 - plasma membrane GO:0007155 - cell adhesion GO:0007156 - homophilic cell adhesion via plasma membrane adhesion molecules GO:0007399 - nervous system development
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 794 Hs			1 795
+	Hs
		1377960 PCDB9_HUMAN (2-794): 0: 980: 72.99		PCDB3_HUMAN (1-795): 0: 968: 74.72
+	Hs
		1377962 PCDB7_HUMAN (2-793): 0: 970: 71.57		PCDBC_HUMAN (1-795): 0: 978: 100.00
+	Hs
		1377961 PCDB7_HUMAN (2-793): 0: 970: 71.57		PCDB3_HUMAN (1-795): 0: 968: 74.72
+	Hs
		1377986 PCDGD_HUMAN (5-790): 0: 909: 41.21		PCDB2_HUMAN (1-795): 0: 965: 74.15
+	Hs
		1377988 PCDBE_HUMAN (2-794): 0: 984: 74.50		PCDAB_HUMAN (24-792): 0: 854: 37.63
+	Hs
		1378028 PCDG8_HUMAN (8-790): 0: 926: 41.80		PCDG5_HUMAN (1-792): 0: 892: 42.67
+	Hs
		1378022 PCDG8_HUMAN (8-790): 0: 926: 41.80		PCDG9_HUMAN (1-792): 0: 891: 42.49
+	Hs
		1378029 PCDG8_HUMAN (8-790): 0: 926: 41.80		PCDG4_HUMAN (1-792): 0: 888: 41.57
+	Hs
		1377994 PCDB1_HUMAN (5-788): 0: 923: 50.44		PCDGI_HUMAN (2-792): 0: 863: 41.69
+	Hs
		1378011 PCDGD_HUMAN (5-790): 0: 909: 41.21		PCDGF_HUMAN (2-794): 0: 868: 41.20
+	Hs
		1350276 PCDGD_HUMAN (5-790): 0: 909: 41.21		PCD10_HUMAN (14-787): 0: 551: 39.28
+	Hs
		1377995 PCDGD_HUMAN (5-790): 0: 909: 41.21		PCDGL_HUMAN (33-730): 4.19e-169: 514: 40.97
+	Hs
		1377967 PCDB6_HUMAN (1-794): 0: 1029: 100.00		PCDB4_HUMAN (1-443): 5.6e-87: 294: 21.86
+	Hs
		1377963 PCDB7_HUMAN (2-793): 0: 970: 71.57		PCDGA_HUMAN (1-443): 9.72e-93: 312: 24.35
+	Hs
		1344893 PCDB6_HUMAN (1-794): 0: 1029: 100.00		PCDBG_HUMAN (348-781): 1.24e-64: 232: 21.05
+	Hs
		1378007 PCDGD_HUMAN (5-790): 0: 909: 41.21		PCDGH_HUMAN (1-443): 1.1e-96: 323: 23.16
+	Hs
		231359 PCDGD_HUMAN (5-790): 0: 909: 41.21		PCDGC_HUMAN (1-443): 9.98e-95: 318: 24.25
+	Hs
		1357401 PCDGD_HUMAN (5-790): 0: 909: 41.21		PCDGG_HUMAN (1-443): 1.72e-92: 311: 23.16
+	Hs
		1344892 PCDB7_HUMAN (2-793): 0: 970: 71.57		PCDBG_HUMAN (348-781): 1.24e-64: 232: 21.05
+	Hs
		1344895 PCDGD_HUMAN (5-790): 0: 909: 41.21		PCDBG_HUMAN (348-781): 1.24e-64: 232: 21.05