HitPredict

Interactor 1: PCDGD (Q9Y5G3)
Protocadherin gamma-B1 (PCDH-gamma-B1)
Gene: PCDHGB1

Interactor 2: PCDGB (Q9Y5H2)
Protocadherin gamma-A11 (PCDH-gamma-A11)
Gene: PCDHGA11

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.811

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Cadherin~Cadherin, Cadherin~Cadherin_2
Common GO terms	GO:0005509 - calcium ion binding GO:0005886 - plasma membrane GO:0007155 - cell adhesion GO:0007156 - homophilic cell adhesion via plasma membrane adhesion molecules GO:0007399 - nervous system development
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 927 Hs			1 935
+	Hs
		1378007 PCDGD_HUMAN (1-912): 0: 1042: 100.00		PCDGH_HUMAN (27-920): 0: 1002: 53.13
+	Hs
		1377995 PCDGD_HUMAN (1-912): 0: 1042: 100.00		PCDGL_HUMAN (15-920): 0: 1001: 47.03
+	Hs
		1357401 PCDGD_HUMAN (1-912): 0: 1042: 100.00		PCDGG_HUMAN (27-920): 0: 990: 52.80
+	Hs
		1378022 PCDG9_HUMAN (1-912): 0: 990: 50.71		PCDG8_HUMAN (4-920): 0: 1035: 73.17
+	Hs
		1378024 PCDG9_HUMAN (1-912): 0: 990: 50.71		PCDG4_HUMAN (1-920): 0: 1025: 73.15
+	Hs
		1378023 PCDG9_HUMAN (1-912): 0: 990: 50.71		PCDG5_HUMAN (1-920): 0: 1024: 73.80
+	Hs
		1377978 PCDG5_HUMAN (1-912): 0: 987: 51.57		PCDB3_HUMAN (1-778): 0: 969: 44.89
+	Hs
		1377986 PCDGD_HUMAN (1-912): 0: 1042: 100.00		PCDB2_HUMAN (6-774): 0: 613: 45.28
+	Hs
		231359 PCDGD_HUMAN (1-912): 0: 1042: 100.00		PCDGC_HUMAN (3-445): 3.81e-101: 339: 25.38
+	Hs
		1378011 PCDGD_HUMAN (1-912): 0: 1042: 100.00		PCDGF_HUMAN (3-445): 1.94e-100: 337: 26.42
+	Hs
		1378012 PCDGD_HUMAN (1-912): 0: 1042: 100.00		PCDGE_HUMAN (3-445): 7.83e-100: 335: 25.98
+	Hs
		1357392 PCDGD_HUMAN (1-912): 0: 1042: 100.00		PCDGK_HUMAN (3-457): 2.6e-96: 326: 24.95
+	Hs
		231360 PCDG9_HUMAN (1-912): 0: 990: 50.71		PCDGC_HUMAN (3-445): 3.81e-101: 339: 25.38
+	Hs
		1378013 PCDG9_HUMAN (1-912): 0: 990: 50.71		PCDGE_HUMAN (3-445): 7.83e-100: 335: 25.98
+	Hs
		1378026 PCDG9_HUMAN (1-912): 0: 990: 50.71		PCDA9_HUMAN (3-444): 3.64e-90: 309: 25.33
+	Hs
		1378019 PCDGD_HUMAN (1-912): 0: 1042: 100.00		PCDG7_HUMAN (2-348): 8.89e-63: 231: 20.61
+	Hs
		1378018 PCDGD_HUMAN (1-912): 0: 1042: 100.00		PCDG9_HUMAN (2-375): 5.64e-62: 229: 20.89
+	Hs
		1378025 PCDG9_HUMAN (1-912): 0: 990: 50.71		PCDG3_HUMAN (2-348): 2.12e-64: 236: 23.68
+	Hs
		1344895 PCDGD_HUMAN (1-912): 0: 1042: 100.00		PCDBG_HUMAN (562-928): 8.01e-12: 71.1: 12.09