HitPredict

Interactor 1: MAFB (Q9Y5Q3)
Transcription factor MafB (Maf-B) (V-maf musculoaponeurotic fibrosarcoma oncogene homolog B)
Gene: MAFB

Interactor 2: MAFB (Q9Y5Q3)
Transcription factor MafB (Maf-B) (V-maf musculoaponeurotic fibrosarcoma oncogene homolog B)
Gene: MAFB

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.91 1.00 0.958

The method score is based on:

Property Details
Experiments 12514174, 15107855, 31822558, 16219768, 12196529, 23661758, 20102225, 20211142
Identification Methods two hybrid, affinity chromatography technology, fluorescent resonance energy transfer, peptide array, two hybrid array
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains bZIP_Maf~bZIP_Maf
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific
and 25 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 323
Hs

1 323
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024