HitPredict

Interactor 1: SNX14 (Q9Y5W7)
Sorting nexin-14
Gene: SNX14

Interactor 2: SNX13 (Q9Y5W8)
Sorting nexin-13 (RGS domain- and PHOX domain-containing protein) (RGS-PX1)
Gene: SNX13

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	1.00	0.665

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PX~PX, RGS~RGS
Common GO terms	GO:0035091 - phosphatidylinositol binding
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 946 Hs			1 968
+	Hs
		207654 AKA10_HUMAN (180-589): 2.53e-52: 197: 15.53		SNX27_HUMAN (548-849): 1.8e-45: 174: 13.40
+	Hs
		1261042 SNX33_HUMAN (503-909): 7.52e-61: 219: 12.56		SNX18_HUMAN (513-802): 3.23e-36: 148: 14.38
+	Hs
		170739 AXIN2_HUMAN (321-678): 3.82e-52: 199: 17.18		AXIN1_HUMAN (291-583): 2.81e-41: 165: 14.24
+	Hs
		1040503 SNX1_HUMAN (471-881): 3.61e-45: 173: 13.77		SNX27_HUMAN (548-849): 1.8e-45: 174: 13.40
+	Mm
		193166 AXIN1_MOUSE (287-574): 3.17e-46: 181: 20.61		AXIN1_MOUSE (291-583): 8.97e-41: 164: 14.56
+	Rn
		250557 AXIN1_RAT (287-609): 3.23e-46: 180: 19.26		AXIN1_RAT (291-583): 5.06e-41: 164: 14.56
+	Hs
		170579 AXIN1_HUMAN (287-668): 5.85e-43: 170: 17.35		AXIN1_HUMAN (291-583): 2.81e-41: 165: 14.24
+	Hs
		1300859 SNX8_HUMAN (587-942): 2.37e-45: 172: 16.26		SNX18_HUMAN (513-802): 3.23e-36: 148: 14.38
+	Hs
		1300849 SNX18_HUMAN (456-852): 9.68e-43: 167: 12.47		SNX18_HUMAN (513-802): 3.23e-36: 148: 14.38
+	Hs
		1256638 SNX29_HUMAN (531-731): 1.45e-24: 112: 19.43		SNX29_HUMAN (281-718): 2.66e-37: 153: 14.01