HitPredict

Interactor 1: SNX9 (Q9Y5X1)
Sorting nexin-9 (SH3 and PX domain-containing protein 1) (Protein SDP1) (SH3 and PX domain-containing protein 3A)
Gene: SNX9

Interactor 2: SNX8 (Q9Y5X2)
Sorting nexin-8
Gene: SNX8

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	23085988
Identification Methods	pull down
Interaction Type	physical association

Property	Details
Interacting Pfam domains	BAR_3_WASP_bdg~PX, PX~PX, PX~Snx8_BAR_dom
Common GO terms	GO:0005829 - cytosol GO:0006886 - intracellular protein transport GO:0035091 - phosphatidylinositol binding
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 595 Hs			1 465
+	Hs
		1261054 SNX9_HUMAN (1-595): 5.31e-180: 523: 100.00		SNX33_HUMAN (4-437): 5.55e-89: 284: 16.21
+	Hs
		1378134 SNX9_HUMAN (1-595): 5.31e-180: 523: 100.00		SNX9_HUMAN (7-418): 2.01e-84: 272: 17.06
+	Hs
		1300858 SNX9_HUMAN (1-595): 5.31e-180: 523: 100.00		SNX18_HUMAN (3-389): 1.44e-83: 271: 17.84
+	Hs
		1261055 SNX33_HUMAN (1-595): 3.41e-135: 407: 34.73		SNX8_HUMAN (1-465): 1.89e-122: 366: 100.00
+	Hs
		1300859 SNX18_HUMAN (1-519): 3.5e-123: 379: 33.09		SNX8_HUMAN (1-465): 1.89e-122: 366: 100.00
+	Hs
		1261036 SNX33_HUMAN (1-595): 3.41e-135: 407: 34.73		SNX33_HUMAN (4-437): 5.55e-89: 284: 16.21
+	Hs
		1261042 SNX33_HUMAN (1-595): 3.41e-135: 407: 34.73		SNX18_HUMAN (3-389): 1.44e-83: 271: 17.84
+	Hs
		1300849 SNX18_HUMAN (1-519): 3.5e-123: 379: 33.09		SNX18_HUMAN (3-389): 1.44e-83: 271: 17.84
+	Dm
		1341910 Q9NCC3_DROME (1-593): 1.61e-127: 387: 31.44		Q9NCC3_DROME (4-434): 3.03e-76: 250: 17.61
+	Hs
		1040542 SNX1_HUMAN (101-590): 7.37e-80: 263: 13.53		SNX8_HUMAN (1-465): 1.89e-122: 366: 100.00
+	Ce
		1211618 LST4_CAEEL (3-593): 9.29e-116: 357: 28.64		LST4_CAEEL (4-437): 6.56e-67: 225: 13.51
+	Hs
		240317 SNX2_HUMAN (110-590): 5.95e-80: 263: 14.74		SNX2_HUMAN (18-443): 1.05e-90: 286: 18.70
+	Hs
		240386 SNX1_HUMAN (101-590): 7.37e-80: 263: 13.53		SNX2_HUMAN (18-443): 1.05e-90: 286: 18.70
+	Hs
		1040456 SNX1_HUMAN (101-590): 7.37e-80: 263: 13.53		SNX1_HUMAN (5-443): 2.41e-84: 270: 16.67
+	Hs
		1040503 SNX1_HUMAN (101-590): 7.37e-80: 263: 13.53		SNX27_HUMAN (3-422): 1.85e-72: 240: 12.86
+	Hs
		1040543 SNX1_HUMAN (101-590): 7.37e-80: 263: 13.53		SNX5_HUMAN (43-442): 2.77e-60: 204: 13.53
+	Hs
		1040533 SNX1_HUMAN (101-590): 7.37e-80: 263: 13.53		SNX6_HUMAN (65-441): 1.6e-56: 194: 13.77