HitPredict

Interactor 1: SAR1B (Q9Y6B6)
Small COPII coat GTPase SAR1B (EC 3.6.5.2) (GTP-binding protein B) (GTBPB) (Secretion-associated Ras-related GTPase 1B)
Gene: SAR1B

Interactor 2: S23IP (Q9Y6Y8)
SEC23-interacting protein (p125)
Gene: SEC23IP

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35844135
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0006886 - intracellular protein transport GO:0006888 - endoplasmic reticulum to Golgi vesicle-mediated transport GO:0012507 - ER to Golgi transport vesicle membrane GO:0046872 - metal ion binding
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 198 Hs			1 1000
+	Hs
		1344239 SAR1A_HUMAN (1-198): 8.78e-63: 194: 89.90		S23IP_HUMAN (1-1000): 0: 1085: 100.00
+	Dm
		897470 ARF1_DROME (1-197): 2.88e-59: 185: 26.90		Q9VLS7_DROME (735-996): 7.37e-50: 195: 40.71
+	Sc
		594400 SAR1_YEAST (4-197): 1.73e-76: 229: 59.79		SEC31_YEAST (6-320): 4.31e-12: 72.7: 13.64
+	Hs
		302324 SAR1A_HUMAN (1-198): 8.78e-63: 194: 89.90		SC31A_HUMAN (8-309): 1.62e-18: 93.5: 12.99
+	Hs
		302334 SAR1B_HUMAN (1-198): 3.26e-59: 185: 100.00		SC31A_HUMAN (8-309): 1.62e-18: 93.5: 12.99
+	Hs
		867133 SAR1A_HUMAN (1-198): 8.78e-63: 194: 89.90		SC24C_HUMAN (33-278): 2.74e-09: 63.5: 17.03
+	Hs
		867145 SAR1B_HUMAN (1-198): 3.26e-59: 185: 100.00		SC24C_HUMAN (33-278): 2.74e-09: 63.5: 17.03