HitPredict

Interactor 1: MD1L1 (Q9Y6D9)
Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient 1-like protein 1) (MAD1-like protein 1) (Mitotic checkpoint MAD1 protein homolog) (HsMAD1) (hMAD1) (Tax-binding protein 181)
Gene: MAD1L1

Interactor 2: MD1L1 (Q9Y6D9)
Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient 1-like protein 1) (MAD1-like protein 1) (Mitotic checkpoint MAD1 protein homolog) (HsMAD1) (hMAD1) (Tax-binding protein 181)
Gene: MAD1L1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.77 1.00 0.878

The method score is based on:

Property Details
Experiments 16189514, 27107012, 22493223
Identification Methods two hybrid, molecular sieving, anti tag coimmunoprecipitation, x-ray crystallography, two hybrid pooling approach
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains MAD~MAD
Common GO terms GO:0000776 - kinetochore
GO:0000922 - spindle pole
GO:0005634 - nucleus
GO:0005635 - nuclear envelope
GO:0005737 - cytoplasm
and 17 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 718
Hs

1 718
+ Sp
+ Hs
+ At
+ Hs
+ Dm
+ Hs
+ Hs
+ Rn
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Sc
+ Mm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024