HitPredict - High confidence protein-protein interactions

Interactor 1: ZNT1 (Q9Y6M5)
Proton-coupled zinc antiporter SLC30A1 (Solute carrier family 30 member 1) (Zinc transporter 1)
Gene: SLC30A1

Interactor 2: ZNT1 (Q9Y6M5)
Proton-coupled zinc antiporter SLC30A1 (Solute carrier family 30 member 1) (Zinc transporter 1)
Gene: SLC30A1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.34	1.00	0.590

Property	Details
Experiments	25657003
Identification Methods	bimolecular fluorescence complementation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Cation_efflux~Cation_efflux
Common GO terms	GO:0001701 - in utero embryonic development GO:0005385 - zinc ion transmembrane transporter activity GO:0005737 - cytoplasm GO:0005783 - endoplasmic reticulum GO:0005794 - Golgi apparatus and 29 others more... GO:0005886 - plasma membrane GO:0006829 - zinc ion transport GO:0006874 - intracellular calcium ion homeostasis GO:0006882 - intracellular zinc ion homeostasis GO:0010312 - detoxification of zinc ion GO:0016323 - basolateral plasma membrane GO:0019855 - calcium channel inhibitor activity GO:0030315 - T-tubule GO:0030425 - dendrite GO:0030659 - cytoplasmic vesicle membrane GO:0031965 - nuclear membrane GO:0042742 - defense response to bacterium GO:0046872 - metal ion binding GO:0046929 - negative regulation of neurotransmitter secretion GO:0061003 - positive regulation of dendritic spine morphogenesis GO:0062111 - zinc ion import into organelle GO:0070509 - calcium ion import GO:0070574 - cadmium ion transmembrane transport GO:0071577 - zinc ion transmembrane transport GO:0071584 - negative regulation of zinc ion transmembrane import GO:0071585 - detoxification of cadmium ion GO:0090281 - negative regulation of calcium ion import GO:0098685 - Schaffer collateral - CA1 synapse GO:0098839 - postsynaptic density membrane GO:0099092 - postsynaptic density, intracellular component GO:0099573 - glutamatergic postsynaptic density GO:0140826 - zinc:proton antiporter activity GO:0140882 - zinc export across plasma membrane GO:1902897 - regulation of postsynaptic density protein 95 clustering
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1	507
Hs

1	507

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Last updated: 15 Jul 2024