HitPredict

Interactor 1: PARD3 (Q9Z340)
Partitioning defective 3 homolog (PAR-3) (PARD-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (Atypical PKC-specific-binding protein) (ASBP)
Gene: PARD3

Interactor 2: PARD3 (Q9Z340)
Partitioning defective 3 homolog (PAR-3) (PARD-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (Atypical PKC-specific-binding protein) (ASBP)
Gene: PARD3

Species: Rattus norvegicus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.53 1.00 0.730

The method score is based on:

Property Details
Experiments 23643951
Identification Methods transmission electron microscopy, atomic force microscopy, molecular sieving, x-ray crystallography, 3D electron microscopy, cross-linking study
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Par3_HAL_N_term~Par3_HAL_N_term, PDZ~PDZ
Common GO terms GO:0000226 - microtubule cytoskeleton organization
GO:0002092 - positive regulation of receptor internalization
GO:0003383 - apical constriction
GO:0005546 - phosphatidylinositol-4,5-bisphosphate binding
GO:0005547 - phosphatidylinositol-3,4,5-trisphosphate binding
and 38 others

more...
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 1337
Rn

1 1337
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Ce
+ Dm
+ Hs
+ Hs
+ Hs
+ Dm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024