HitPredict

Interactor 1: FTN (Q9ZLI1)
Bacterial non-heme ferritin (EC 1.16.3.2)
Gene: ftnA

Interactor 2: FTN (Q9ZLI1)
Bacterial non-heme ferritin (EC 1.16.3.2)
Gene: ftnA

Species: Helicobacter pylori J99

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.63	1.00	0.794

Property	Details
Experiments	17092930, 23698367
Identification Methods	blue native page, molecular sieving, dynamic light scattering, transmission electron microscopy
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	Ferritin~Ferritin
Common GO terms	GO:0004322 - ferroxidase activity GO:0005829 - cytosol GO:0006826 - iron ion transport GO:0006880 - intracellular sequestering of iron ion GO:0008198 - ferrous iron binding and 1 others more... GO:0008199 - ferric iron binding
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 167 Hp			1 167
+	Hs
		365121 FRIH_HUMAN (2-160): 4.51e-64: 196: 23.03		FRIH_HUMAN (2-160): 4.51e-64: 196: 23.03
+	Mm
		451809 FRIH_MOUSE (2-160): 4.18e-64: 196: 23.64		FRIH_MOUSE (2-160): 4.18e-64: 196: 23.64
+	Hs
		1157509 Q6NZ44_HUMAN (2-160): 4.02e-63: 193: 23.03		Q6NZ44_HUMAN (2-160): 4.02e-63: 193: 23.03
+	At
		1107009 FRI1_ARATH (2-160): 8.24e-61: 190: 24.55		FRI1_ARATH (2-160): 8.24e-61: 190: 24.55
+	At
		1107014 FRI1_ARATH (2-160): 8.24e-61: 190: 24.55		FRI3_ARATH (1-162): 2e-59: 187: 24.12
+	Hp
		852330 FTN_HELPY (1-167): 2.37e-61: 188: 98.20		FTN_HELPY (1-167): 2.37e-61: 188: 98.20
+	Hs
		364816 FRIH_HUMAN (2-160): 4.51e-64: 196: 23.03		FRIL_HUMAN (2-159): 6.75e-57: 177: 18.90
+	Mm
		451814 FRIH_MOUSE (2-160): 4.18e-64: 196: 23.64		Q9CPX4_MOUSE (2-159): 6.75e-57: 177: 16.86
+	Hs
		364926 Q6NZ44_HUMAN (2-160): 4.02e-63: 193: 23.03		FRIL_HUMAN (2-159): 6.75e-57: 177: 18.90
+	Ce
		1353436 Q9TYS3_CAEEL (2-157): 3.79e-58: 180: 24.38		Q9TYS3_CAEEL (2-157): 3.79e-58: 180: 24.38
+	Mm
		1321681 Q9CPX4_MOUSE (2-159): 6.75e-57: 177: 16.86		Q9CPX4_MOUSE (2-159): 6.75e-57: 177: 16.86
+	Af
		191424 O29424_ARCFU (2-158): 5.56e-57: 177: 36.31		O29424_ARCFU (2-158): 5.56e-57: 177: 36.31
+	Hs
		364815 FRIL_HUMAN (2-159): 6.75e-57: 177: 18.90		FRIL_HUMAN (2-159): 6.75e-57: 177: 18.90
+	Ce
		183900 Q9TYS3_CAEEL (2-157): 3.79e-58: 180: 24.38		O16453_CAEEL (2-157): 5.31e-55: 172: 23.75
+	Dm
		1375733 Q9VYH1_DROME (2-158): 9.24e-55: 172: 24.38		Q9VYH1_DROME (2-158): 9.24e-55: 172: 24.38
+	Ce
		183894 O16453_CAEEL (2-157): 5.31e-55: 172: 23.75		O16453_CAEEL (2-157): 5.31e-55: 172: 23.75