HitPredict

Interactor 1: P2C77 (O04719)
Protein phosphatase 2C 77 (AtPP2C77) (EC 3.1.3.16) (Protein ABSCISIC ACID-INSENSITIVE 2) (Protein phosphatase 2C ABI2) (PP2C ABI2)
Gene: ABI2

Interactor 2: PYR1 (O49686)
Abscisic acid receptor PYR1 (ABI1-binding protein 6) (Protein PYRABACTIN RESISTANCE 1) (Regulatory components of ABA receptor 11)
Gene: PYR1

Species: Arabidopsis thaliana

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.77	1.00	0.882

Property	Details
Experiments	19407142, 20729862, 19898420
Identification Methods	two hybrid, affinity chromatography technology, pull down, amplified luminescent proximity homogeneous assay, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	PP2C~Polyketide_cyc2
Common GO terms	GO:0005634 - nucleus GO:0009738 - abscisic acid-activated signaling pathway
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 423 At			1 191
+	At
		138635 P2C77_ARATH (1-423): 1.96e-171: 488: 100.00		PYL9_ARATH (15-185): 3.06e-94: 273: 45.03
+	At
		138646 P2C77_ARATH (1-423): 1.96e-171: 488: 100.00		PYL8_ARATH (14-186): 8.81e-91: 264: 45.67
+	At
		138636 P2C77_ARATH (1-423): 1.96e-171: 488: 100.00		PYL10_ARATH (5-182): 8.99e-88: 257: 42.46
+	At
		138648 P2C77_ARATH (1-423): 1.96e-171: 488: 100.00		PYL5_ARATH (13-178): 1.17e-85: 252: 51.21
+	At
		138619 P2C77_ARATH (1-423): 1.96e-171: 488: 100.00		PYL2_ARATH (4-182): 5.46e-84: 248: 53.59
+	At
		138637 P2C77_ARATH (1-423): 1.96e-171: 488: 100.00		PYL6_ARATH (12-182): 3.15e-83: 246: 49.13
+	At
		138639 P2C77_ARATH (1-423): 1.96e-171: 488: 100.00		PYL1_ARATH (1-190): 3e-82: 244: 76.17
+	At
		138654 P2C77_ARATH (1-423): 1.96e-171: 488: 100.00		PYL3_ARATH (2-177): 2.06e-82: 244: 50.81
+	At
		138618 P2C77_ARATH (1-423): 1.96e-171: 488: 100.00		PYL4_ARATH (14-182): 2.38e-80: 239: 54.44
+	At
		221991 P2C56_ARATH (1-423): 5.72e-144: 418: 70.52		PYR1_ARATH (1-191): 2.28e-99: 286: 100.00
+	At
		829503 P2C56_ARATH (1-423): 5.72e-144: 418: 70.52		PYL9_ARATH (15-185): 3.06e-94: 273: 45.03
+	At
		138647 P2C77_ARATH (1-423): 1.96e-171: 488: 100.00		PYL11_ARATH (28-179): 3.83e-65: 199: 52.63
+	At
		829492 P2C56_ARATH (1-423): 5.72e-144: 418: 70.52		PYL7_ARATH (15-186): 2.41e-92: 269: 48.26
+	At
		829518 P2C56_ARATH (1-423): 5.72e-144: 418: 70.52		PYL8_ARATH (14-186): 8.81e-91: 264: 45.67
+	At
		829504 P2C56_ARATH (1-423): 5.72e-144: 418: 70.52		PYL10_ARATH (5-182): 8.99e-88: 257: 42.46
+	At
		138653 P2C77_ARATH (1-423): 1.96e-171: 488: 100.00		PYL13_ARATH (27-180): 5.79e-57: 178: 47.80
+	At
		286072 P2C56_ARATH (1-423): 5.72e-144: 418: 70.52		PYL2_ARATH (4-182): 5.46e-84: 248: 53.59
+	At
		829507 P2C56_ARATH (1-423): 5.72e-144: 418: 70.52		PYL6_ARATH (12-182): 3.15e-83: 246: 49.13
+	At
		829510 P2C56_ARATH (1-423): 5.72e-144: 418: 70.52		PYL1_ARATH (1-190): 3e-82: 244: 76.17
+	At
		285957 P2C56_ARATH (1-423): 5.72e-144: 418: 70.52		PYL4_ARATH (14-182): 2.38e-80: 239: 54.44