Interactor 1: SIR1 (Q96EB6)
NAD-dependent protein deacetylase sirtuin-1 (hSIRT1) (EC 2.3.1.286) (NAD-dependent protein deacylase sirtuin-1) (EC 2.3.1.-) (Regulatory protein SIR2 homolog 1) (SIR2-like protein 1) (hSIR2) [Cleaved into: SirtT1 75 kDa fragment (75SirT1)]
Gene: SIRT1
Interactor 2: CHCH2 (Q9Y6H1)
Coiled-coil-helix-coiled-coil-helix domain-containing protein 2 (Aging-associated gene 10 protein) (HCV NS2 trans-regulated protein) (NS2TP)
Gene: CHCHD2
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.44 | 0.55 | 0.493 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 19343720 |
| Identification Methods | affinity chromatography technology, pull down |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0005634 - nucleus GO:0005739 - mitochondrion GO:0045944 - positive regulation of transcription by RNA polymerase II GO:0140297 - DNA-binding transcription factor binding |
| Homologous interactions | 0 |
Service provided by Combinatics, Japan
Last updated: 11Aug2025
