HitPredict

Interactor 1: BIN1 (O08539)
Myc box-dependent-interacting protein 1 (Amphiphysin II) (Amphiphysin-like protein) (Bridging integrator 1) (SH3 domain-containing protein 9)
Gene: BIN1

Interactor 2: DYN3 (Q8BZ98)
Dynamin-3 (EC 3.6.5.5)
Gene: Dnm3

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	23640057
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PH~SH3_9
Common GO terms	GO:0005874 - microtubule GO:0005886 - plasma membrane GO:0030424 - axon GO:0045202 - synapse GO:0048488 - synaptic vesicle endocytosis and 1 others more... GO:0098978 - glutamatergic synapse
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 588 Mm			1 863
+	Mm
		139028 BIN1_MOUSE (1-588): 7.74e-167: 489: 100.00		DYN1_MOUSE (1-841): 0: 1019: 78.99
+	Mm
		139029 BIN1_MOUSE (1-588): 7.74e-167: 489: 100.00		DYN2_MOUSE (1-863): 0: 1014: 79.04
+	Rn
		139987 BIN1_RAT (1-588): 4.1e-165: 485: 99.15		DYN1_RAT (1-846): 0: 1013: 78.41
+	Hs
		131238 BIN1_HUMAN (1-587): 1.67e-155: 460: 94.60		DYN1_HUMAN (1-846): 0: 1020: 78.65
+	Hs
		131222 BIN1_HUMAN (1-587): 1.67e-155: 460: 94.60		DYN2_HUMAN (1-863): 0: 1017: 79.04
+	Mm
		1186718 AMPH_MOUSE (9-588): 1.79e-93: 303: 35.71		DYN3_MOUSE (1-863): 0: 1066: 100.00
+	Mm
		760459 AMPH_MOUSE (9-588): 1.79e-93: 303: 35.71		DYN1_MOUSE (1-841): 0: 1019: 78.99
+	Mm
		760477 AMPH_MOUSE (9-588): 1.79e-93: 303: 35.71		DYN2_MOUSE (1-863): 0: 1014: 79.04
+	Rn
		139973 AMPH_RAT (9-547): 1.99e-92: 300: 44.86		DYN1_RAT (1-846): 0: 1013: 78.41
+	Rn
		139974 AMPH_RAT (9-547): 1.99e-92: 300: 44.86		DYN2_RAT (1-863): 0: 1011: 78.93
+	Hs
		1167839 DNMBP_HUMAN (17-584): 1.07e-76: 267: 14.14		DYN3_HUMAN (1-863): 0: 1041: 96.33
+	Hs
		983387 DNMBP_HUMAN (17-584): 1.07e-76: 267: 14.14		DYN1_HUMAN (1-846): 0: 1020: 78.65
+	Hs
		840739 DNMBP_HUMAN (17-584): 1.07e-76: 267: 14.14		DYN2_HUMAN (1-863): 0: 1017: 79.04
+	Hs
		827766 AMPH_HUMAN (84-588): 8.64e-21: 98.7: 18.98		DYN3_HUMAN (1-863): 0: 1041: 96.33
+	Hs
		983422 CABIN_HUMAN (271-535): 1.17e-24: 111: 13.76		DYN1_HUMAN (1-846): 0: 1020: 78.65
+	Hs
		827736 AMPH_HUMAN (84-588): 8.64e-21: 98.7: 18.98		DYN1_HUMAN (1-846): 0: 1020: 78.65
+	Hs
		827729 AMPH_HUMAN (84-588): 8.64e-21: 98.7: 18.98		DYN2_HUMAN (1-863): 0: 1017: 79.04
+	Sc
		599466 RV167_YEAST (16-400): 9.74e-59: 205: 14.74		VPS1_YEAST (7-658): 0: 658: 37.23