Interactor 1: EFNA5 (O08543)
Ephrin-A5 (AL-1) (EPH-related receptor tyrosine kinase ligand 7) (LERK-7)
Gene: EFNA5

Interactor 2: EPHB2 (P54763)
Ephrin type-B receptor 2 (EC 2.7.10.1) (Neural kinase) (Nuk receptor tyrosine kinase) (Tyrosine-protein kinase receptor EPH-3) (Tyrosine-protein kinase receptor SEK-3) [Cleaved into: EphB2/CTF1; EphB2/CTF2]
Gene: EPHB2

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 1.00 0.647

The method score is based on:

Property Details
Experiments 15107857
Identification Methods x-ray crystallography
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Ephrin~Ephrin_lbd
Common GO terms GO:0005886 - plasma membrane
GO:0007411 - axon guidance
GO:0031290 - retinal ganglion cell axon guidance
GO:0048013 - ephrin receptor signaling pathway
GO:0051965 - positive regulation of synapse assembly
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 228
Mm

1 986
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Last updated: 15 Jul 2024