HitPredict

Interactor 1: DPYL2 (O08553)
Dihydropyrimidinase-related protein 2 (DRP-2) (Unc-33-like phosphoprotein 2) (ULIP-2)
Gene: Dpysl2

Interactor 2: DPYL5 (Q9EQF6)
Dihydropyrimidinase-related protein 5 (DRP-5) (Collapsin response mediator protein 5) (CRMP-5)
Gene: Dpysl5

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.50	1.00	0.713

Property	Details
Experiments	10956643
Identification Methods	two hybrid, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	Amidohydro_1~Amidohydro_1
Common GO terms	GO:0005829 - cytosol GO:0016812 - hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides GO:0030425 - dendrite GO:0032991 - protein-containing complex GO:0043025 - neuronal cell body
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 572 Mm			1 564
+	Hs
		1050867 DPYL2_HUMAN (1-572): 0: 780: 98.78		DPYL1_HUMAN (6-561): 0: 709: 50.99
+	Hs
		1083101 DPYL2_HUMAN (1-572): 0: 780: 98.78		DPYL2_HUMAN (6-561): 0: 708: 50.99
+	Mm
		139071 DPYL2_MOUSE (1-572): 0: 779: 100.00		DPYL2_MOUSE (6-561): 0: 707: 51.53
+	Rn
		815101 DPYL2_RAT (1-572): 0: 779: 100.00		DPYL2_RAT (6-561): 0: 707: 51.53
+	Hs
		1083135 DPYL2_HUMAN (1-572): 0: 780: 98.78		DPYL5_HUMAN (1-564): 0: 705: 97.87
+	Hs
		1083161 DPYL2_HUMAN (1-572): 0: 780: 98.78		X5DQV1_HUMAN (4-561): 0: 705: 50.98
+	Hs
		1050916 DPYL2_HUMAN (1-572): 0: 780: 98.78		DPYL3_HUMAN (6-561): 0: 702: 50.90
+	Mm
		139110 DPYL2_MOUSE (1-572): 0: 779: 100.00		DPYL1_MOUSE (6-561): 0: 702: 50.45
+	Hs
		1083118 DPYL2_HUMAN (1-572): 0: 780: 98.78		Q8IXW6_HUMAN (6-561): 0: 700: 50.72
+	Hs
		1050860 DPYL1_HUMAN (1-572): 0: 770: 76.40		DPYL1_HUMAN (6-561): 0: 709: 50.99
+	Hs
		147335 DPYL2_HUMAN (1-572): 0: 780: 98.78		DPYL4_HUMAN (6-561): 0: 699: 50.00
+	Hs
		1050861 DPYL1_HUMAN (1-572): 0: 770: 76.40		DPYL3_HUMAN (6-561): 0: 702: 50.90
+	Hs
		147331 DPYL1_HUMAN (1-572): 0: 770: 76.40		DPYL4_HUMAN (6-561): 0: 699: 50.00
+	Mm
		956442 DPYL1_MOUSE (1-572): 0: 761: 76.22		Q3TMU8_MOUSE (6-561): 0: 700: 50.72
+	Mm
		956446 DPYL1_MOUSE (1-572): 0: 761: 76.22		DPYL3_MOUSE (6-561): 0: 699: 51.08
+	Hs
		147332 DPYL3_HUMAN (1-571): 0: 755: 77.41		DPYL4_HUMAN (6-561): 0: 699: 50.00
+	Hs
		1048473 DPYL2_HUMAN (1-572): 0: 780: 98.78		DPYS_HUMAN (5-518): 0: 644: 57.34
+	Hs
		1048471 DPYL3_HUMAN (1-571): 0: 755: 77.41		DPYS_HUMAN (5-518): 0: 644: 57.34